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- Title
CNS germinoma with extensive calcification: An unusual histologic finding.
- Authors
TAN, Geok Chin; SALLAPAN, Sugunah; HAWORTH, Kellie; FINLAY, Jonathan; BOUE', Daniel R.; PIERSON, Christopher R.
- Abstract
Introduction: Intratumoral calcification is a feature that is more often observed in pineal parenchymal tumour than germinoma. We describe a 13-year-old male with pineal region germinoma demonstrating extensive intratumoral calcification. Case report: He presented with worsening headache that was associated with fatigue, nausea and vomiting. Radiologic examination revealed a multilobular mass in the pineal region with internal calcifications. Biopsy showed a pure germinoma with unusually extensive calcification. Discussion: Although a diagnosis may be suggested with a careful evaluation of imaging, there is no pathognomonic pattern. Thus, histologic verification is necessary for most pineal region masses.
- Subjects
GERMINOMA; CALCIFICATION; CANCER; MIGRAINE aura
- Publication
Malaysian Journal of Pathology, 2019, Vol 41, Issue 1, p71
- ISSN
0126-8635
- Publication type
Article