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- Title
Complications of deep brain stimulation for secondary dystonia in the early postoperative period (30-day morbidity): experience in 49 patients.
- Authors
Wloch, Andreas; Mahmoud, Abdallat; Saryyeva, Assel; Blahak, Christoph; Wolf, Marc; Schrader, Christoph; Runge, Joachim; Krauss, Joachim K.
- Abstract
Objective: Deep brain stimulation (DBS) has been shown to be efficacious in the treatment of primary dystonia (idiopathic and inherited dystonia). There is less experience in, however, secondary dystonia (acquired dystonia). Since patients with secondary dystonia, who are often more disabled, may be more vulnerable to postoperative complications we aimed to investigate the 30- day morbidity in a large cohort of patients with secondary dystonia operated over a period of 19 years. Methods: From 1997 until 2016, a total of 49 patients (27 women and 22 men; mean age 43,5 years (range 13-77)) with secondary dystonia underwent DBS with electrodes implanted either in the thalamic Nucl. ventralis intermedius (Vim) or the posteroventral lateral globus pallidus internus (GPi). Most frequent cause of for dystonia was cerebral palsy in 17 patients. Results: There were no intraoperative complications or complications in the early postoperative period related to surgery. The electrode location was corrected in 2 instances. Two patients developed a wound infection, one patient had a subdural hematoma and subcutaneous collection of cerebrospinal fluid (CSF). Three weeks after DBS the subdural hematoma and CSF resolved. Conclusion: The 30-day morbidity rate in DBS for secondary dystonia is comparable to that in primary dystonia. DBS surgery may be offered to patients with secondary dystonia without concerns about higher morbidity.
- Publication
Stereotactic & Functional Neurosurgery, 2017, Vol 95, p240
- ISSN
1011-6125
- Publication type
Article