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- Title
Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy.
- Authors
Spatola, Corrado; Liardo, Rocco Luca Emanuele; Milazzotto, Roberto; Raffaele, Luigi; Salamone, Vincenzo; Basile, Antonio; Foti, Pietro Valerio; Palmucci, Stefano; Cirrone, Giuseppe Antonio Pablo; Cuttone, Giacomo; Russo, Andrea; Avitabile, Teresio; Reibaldi, Michele; Longo, Antonio; Broggi, Giuseppe; Bonfiglio, Vincenza; Caltabiano, Rosario; Pergolizzi, Stefano; Arena, Floriana
- Abstract
Conjunctival melanoma is a rare neoplasia, whose therapeutic management is generally of ophthalmological relevance, through radical surgical resection. The high incidence of local relapses after surgery, has made it necessary to combine various types of adjuvant treatments, which in some cases take on the role of radical treatments. Among these non-surgical treatments, those involving the application of ionizing radiation are becoming particularly important. In this review, we discuss the role of episcleral brachytherapy, external photon-beam radiotherapy, also made through stereotactic or radiosurgical modality, and of proton-beam radiotherapy. We try also to take stock of the benefits of the different irradiation modalities and the application difficulties of each.
- Subjects
RADIOISOTOPE brachytherapy; RADIOTHERAPY; MELANOMA; IONIZING radiation; SURGICAL excision; PHOTON beams; PROTON beams
- Publication
Applied Sciences (2076-3417), 2020, Vol 10, Issue 24, p9071
- ISSN
2076-3417
- Publication type
Article
- DOI
10.3390/app10249071