We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Factors regulating fat oxidation in human skeletal muscle.
- Authors
Kiens, B.; Alsted, T. J.; Jeppesen, J.
- Abstract
Summary In modern societies, oversupply of calories leads to obesity and chronic metabolic stress, which may lead to development of disease. Oversupply of calories is often associated with elevated plasma lipid concentrations and accumulation of lipids in skeletal muscle leading to decreased insulin sensitivity. Consequently, enhanced fat oxidation might be beneficial in counteracting lipid accumulation. Exercise is the most effective way to increase fat oxidation, because it increases metabolic rate. Lipid metabolism can also be altered by dietary manipulations. Thus, a fat rich diet leads to increased potential for fat oxidation by increasing the content of several of the proteins in the fat oxidative pathway. The regulation of both exercise and diet induced lipid oxidation will be discussed in this review.
- Subjects
SKELETAL muscle; HUMAN skeleton; OBESITY; LIPID metabolism disorders; BLOOD lipids
- Publication
Obesity Reviews, 2011, Vol 12, Issue 10, p852
- ISSN
1467-7881
- Publication type
Article
- DOI
10.1111/j.1467-789X.2011.00898.x