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- Title
Significant Differential Effects of Alendronate, Estrogen, or Combination Therapy on the Rate of Bone Loss after Discontinuation of Treatment of Postmenopausal Osteoporosis.
- Authors
Greenspan, Susan L.; Emkey, Ronald D.; Bone III, Henry G.; Weiss, Stuart R.; Bell, Norman H.; Downs, Robert W.; McKeever, Clark; Miller, Sam S.; Davidson, Michael; Bolognese, Michael A.; Mulloy, Anthony L.; Heyden, Norman; Mei Wu; Kaur, Amarjot
- Abstract
Determines the rate of bone loss when therapy with alendronate, estrogen or both agents is discontinued. Result of bone mineral density and boimechanical markers of bone turnover; Conclusion that accelerated bone loss is seen after withdrawal of estrogen therapy but not after withdrawal of alendronate or combination therapy.
- Subjects
OSTEOPOROSIS; ESTROGEN replacement therapy
- Publication
Annals of Internal Medicine, 2002, Vol 137, Issue 11, p875
- ISSN
0003-4819
- Publication type
Article
- DOI
10.7326/0003-4819-137-11-200212030-00008