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- Title
Clear cell variant of calcifying epithelial odontogenic tumor (CEOT) in the maxilla: report of a case with immunohistochemical and ultrastructural investigations.
- Authors
Kumamoto, Hiroyuki; Sato, Ikuro; Tateno, Hiroo; Yokoyama, Junkichi; Takahashi, Tetsu; Ooya, Kiyoshi; Kumamoto, H; Sato, I; Tateno, H; Yokoyama, J; Takahashi, T; Ooya, K
- Abstract
A rare case of clear cell variant of calcifying epithelial odontogenic tumor is presented with immunohistochemical and ultrastructural investigations. A 14-year-old Japanese girl was admitted with a complaint of swelling in the right posterior maxilla. Radiological examination showed a well-circumscribed radiolucent lesion located close to the impacted third molar. After only a partial tumor excision, the tumor recurred 13 years later. It appeared radiologically as an irregular radiodensity, and a subtotal maxillectomy was performed. Histological examination showed sheets and/or strands composed almost entirely of clear vacuolated epithelial cells in a stroma containing intercellular amyloid-like material and calcification. Histochemical and ultrastructural analysis detected cytoplasmic glycogen granules in the clear cells, and positive immunoreactivities for cytokeratins 8, 13 and 19; filaggrin and anti-ameloblastoma antibodies suggested an odontogenic epithelial origin.
- Subjects
CELLS; TUMORS; MAXILLA; GLYCOGEN; IMMUNOGLOBULINS; EPITHELIUM; PROTEIN analysis; IMMUNOGLOBULIN analysis; CYTOPLASM; CYTOSKELETAL proteins; ELECTRON microscopy; EPITHELIAL cells; IMMUNOHISTOCHEMISTRY; ODONTOGENIC tumors; MAXILLARY tumors; CALCINOSIS
- Publication
Journal of Oral Pathology & Medicine, 1999, Vol 28, Issue 4, p187
- ISSN
0904-2512
- Publication type
journal article
- DOI
10.1111/j.1600-0714.1999.tb02022.x