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- Title
Immunohistochemical observations on a possible ameloblastic fibro-odontoma.
- Authors
Miyauchi, Mutsumi; Takata, Takashi; Ogawa, Ikuko; Ito, Hiroshi; Nikai, Hiromasa; Ijuhin, Naokuni; Tanimoto, Keiji; Miyauchi, Shinobu; Miyauchi, M; Takata, T; Ogawa, I; Ito, H; Nikai, H; Ijuhin, N; Tanimoto, K; Miyauchi, S
- Abstract
An ameloblastic fibro-odontoma which occurred in the mandible of a 3-year-old Japanese boy is reported together with immunohistochemical findings. Histologically, the tumor consisted of an ameloblastic fibroma-like area and some typical complex odontoma-like areas. The epithelial islands in the ameloblastic fibroma-like area showed different developmental stages of the epithelial-connective tissue interface. Immunohistochemical examination revealed that all epithelial components in the ameloblastic fibroma-like area showed expression of CK 8, CKs 13, 16, CK 14, CK 18 and CK 19, and coexpression of these cytokeratins and vimentin. These findings suggest that even the epithelial component without obvious epithelial-mesenchymal induction showed the final cell differentiation of the enamel organ with the potential for epithelial-mesenchymal induction.
- Subjects
JAW tumors; FIBROMAS; MANDIBLE; IMMUNOHISTOCHEMISTRY; EPITHELIUM; MESENCHYME; PROTEIN analysis; CANCER; CELL differentiation; CONNECTIVE tissues; CYTOSKELETAL proteins; ODONTOGENIC tumors; TEETH; EMBRYOS
- Publication
Journal of Oral Pathology & Medicine, 1996, Vol 25, Issue 2, p93
- ISSN
0904-2512
- Publication type
journal article
- DOI
10.1111/j.1600-0714.1996.tb00200.x