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Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling.
- Published in:
- EMBO Molecular Medicine, 2020, v. 12, n. 11, p. 1, doi. 10.15252/emmm.201911776
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- Article
The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Aβ generation in vivo.
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- EMBO Journal, 2006, v. 25, n. 2, p. 432, doi. 10.1038/sj.emboj.7600938
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- Article
Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation.
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- EMBO Journal, 2005, v. 24, n. 9, p. 1706, doi. 10.1038/sj.emboj.7600650
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- Article
Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of protein-lipid complexes.
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- EMBO Journal, 1999, v. 18, n. 7, p. 1761, doi. 10.1093/emboj/18.7.1761
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- Article
Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9756, doi. 10.3390/ijms24119756
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- Article
Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains.
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- 2003
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- Publication type:
- Report
Brain plasmin enhances APP a-cleavage and Aß degradation and is reduced in Alzheimer's disease brains.
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- EMBO Reports, 2000, v. 1, n. 6, p. 530, doi. 10.1093/embo-reports/kvd107
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- Article
Lipid dynamics at dendritic spines.
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- Frontiers in Neuroanatomy, 2014, v. 8, p. 1, doi. 10.3389/fnana.2014.00076
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- Article
Neuronal membrane cholesterol loss enhances amyloid peptide generation.
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- Journal of Cell Biology, 2004, v. 167, n. 5, p. 953, doi. 10.1083/jcb.200404149
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- Article
Prion Protein Accumulation in Lipid Rafts of Mouse Aging Brain.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074244
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- Article
Synaptic Vesicle Docking: Sphingosine Regulates Syntaxin1 Interaction with Munc18.
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- PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005310
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- Article
Plasmin Deficiency in Alzheimer's Disease Brains: Causal or Casual?
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- Neurodegenerative Diseases, 2004, v. 1, n. 4/5, p. 205, doi. 10.1159/000080987
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- Publication type:
- Article
NPC1 enables cholesterol mobilization during long‐term potentiation that can be restored in Niemann–Pick disease type C by CYP46A1 activation.
- Published in:
- EMBO Reports, 2019, v. 20, n. 11, p. N.PAG, doi. 10.15252/embr.201948143
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- Publication type:
- Article
Lipid‐induced lysosomal damage after demyelination corrupts microglia protective function in lysosomal storage disorders.
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- EMBO Journal, 2019, v. 38, n. 2, p. N.PAG, doi. 10.15252/embj.201899553
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- Article
Multifaceted Role of Sialylation in Prion Diseases.
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- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00358
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- Article
Endocytosis of NBD-Sphingolipids in Neurons: Exclusion from Degradative Compartments and Transport to the Golgi Complex.
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- Traffic, 2001, v. 2, n. 6, p. 395, doi. 10.1034/j.1600-0854.2001.002006395.x
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- Article
Adeno-associated viral vector serotype 9–based gene therapy for Niemann-Pick disease type A.
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- Science Translational Medicine, 2019, v. 11, n. 506, p. 1, doi. 10.1126/scitranslmed.aat3738
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- Article
Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice.
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- Journal of Neurochemistry, 2011, v. 116, n. 5, p. 779, doi. 10.1111/j.1471-4159.2010.07034.x
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- Publication type:
- Article
WIP modulates dendritic spine actin cytoskeleton by transcriptional control of lipid metabolic enzymes.
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- Human Molecular Genetics, 2014, v. 23, n. 16, p. 4383, doi. 10.1093/hmg/ddu155
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- Article
Editorial: Lipids in the Brain.
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- 2020
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- Publication type:
- Editorial
Sphingomyelin 16:0 is a therapeutic target for neuronal death in acid sphingomyelinase deficiency.
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- Cell Death & Disease, 2023, v. 14, n. 4, p. 1, doi. 10.1038/s41419-023-05784-2
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- Publication type:
- Article
CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease.
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- Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00780-0
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- Publication type:
- Article
Amyloid excess in Alzheimer’s disease: What is cholesterol to be blamed for?
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- FEBS Letters, 2006, v. 580, n. 23, p. 5525, doi. 10.1016/j.febslet.2006.06.038
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- Publication type:
- Article