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- Title
Cardiac biomarkers for diagnosing Takotsubo syndrome.
- Authors
Schweiger, Victor; Vece, Davide Di; Cammann, Victoria L; Koleva, Iva; Würdinger, Michael; Gilhofer, Thomas; Rajman, Katja; Szawan, Konrad A; Niederseer, David; Citro, Rodolfo; Vecchione, Carmine; Bossone, Eduardo; Gili, Sebastiano; Neuhaus, Michael; Franke, Jennifer; Meder, Benjamin; Jaguszewski, Miłosz; Noutsias, Michel; Knorr, Maike; Jansen, Thomas
- Abstract
This article examines the use of cardiac biomarkers to diagnose Takotsubo syndrome (TTS), a condition characterized by abnormal left ventricular wall motion. The study validates previously proposed ratios of cardiac biomarkers in distinguishing TTS from acute coronary syndrome (ACS) using data from the International Takotsubo (InterTAK) Registry. The results indicate that these ratios have moderate success in accurately diagnosing TTS, with values ranging from 0.5 to 0.8 on the receiver-operating characteristic (ROC) curve. The study emphasizes the need for new biomarkers to improve TTS diagnosis. The article also includes financial disclosures from the authors, ensuring transparency and avoiding conflicts of interest. The authors state that they have no funding for the current contribution and have obtained ethical approval for the study, providing the pre-registered clinical trial number.
- Subjects
TAKOTSUBO cardiomyopathy; ST elevation myocardial infarction; BIOMARKERS; DIAGNOSIS
- Publication
European Heart Journal, 2024, Vol 45, Issue 25, p2254
- ISSN
0195-668X
- Publication type
Article
- DOI
10.1093/eurheartj/ehae231