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- Title
Representation of Functional Category in the Monkey Prefrontal Cortex and Its Rule-Dependent Use for Behavioral Selection.
- Authors
Ken-Ichiro Tsutsui; Takayuki Hosokawa; Munekazu Yamada; Toshio Iijima
- Abstract
Humans, monkeys, and other animals are considered to have the cognitive ability to use functional categories--that is, stimulus groups based on functional equivalence independent of physical properties. To investigate the underlying neural mechanisms of the use of functional categories, we recorded single-unit activity in the prefrontal cortex of monkeys performing a behavioral task in which the rule-dependent usage of functional category was needed to select an appropriate response. We found a neural correlate of functional categories on the single-neuron level and found that category information is coded independently of other task-relevant information such as rule and contingency information. Analysis of the time course of the information activation suggested that contingency information used for action selection is derived by integrating incoming category information with rule information maintained throughout a session. Such neural computation can be considered as the neural background of flexible behavioral control based on category and rule.
- Subjects
PREFRONTAL cortex; BEHAVIORAL research; BRAIN function localization; COGNITIVE ability; NEUROPHYSIOLOGY; PHYSIOLOGY
- Publication
Journal of Neuroscience, 2016, Vol 36, Issue 10, p3038
- ISSN
0270-6474
- Publication type
Article
- DOI
10.1523/JNEUROSCI.2063-15.2016