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- Title
Cirrhosis: A Risk Factor for Cryptococcal Peritonitis.
- Authors
Mabee, Christopher L.; Mabee, Scott W.; Kirkpatrick, Robert B.; Koletar, Susan L.
- Abstract
Cryptococcal peritonitis is usually associated with end-stage renal disease and peritoneal dialysis. Significant liver disease has not been well recognized as a risk factor for its development. We report two patients with cirrhosis who developed peritoneal infections with <em>Cryptococcus neoformans</em>. We also retrospectively review all cases of cryptococcal illness at the Ohio State University Medical Center from October 1990 to January 1994 and present a review of the literature regarding cryptococcal peritonitis associated with hepatic dysfunction. Cirrhotic patients with this entity present with subtle, nonspecific complaints resulting in delayed diagnoses, dissemination, and death. We suggest that clinicians maintain an increased awareness of this unusual but lethal entity in patients with liver impairment. Early and frequent abdominal paracenteses with bedside inoculations of fungal culture medium, India ink preparations, and serum cryptococcal antigen testing may hasten the diagnosis and institution of appropriate therapy.
- Subjects
CRYPTOCOCCALES; PERITONITIS; PERITONEUM diseases; CHRONIC kidney failure; PERITONEAL dialysis; LIVER diseases; CIRRHOSIS of the liver; STOMACH infections; CRYPTOCOCCUS
- Publication
American Journal of Gastroenterology (Springer Nature), 1995, Vol 90, Issue 11, p2042
- ISSN
0002-9270
- Publication type
Article