We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A clinical trial on topical effect of probiotics on oral counts in children.
- Authors
Patil, Raju; Nachan, Vedashri; Patil, Sameer; Mhaske, Rahul; Patil, Raju Umaji; Nachan, Vedashri Prashant; Patil, Sameer S; Mhaske, Rahul Vasantrao
- Abstract
<bold>Background: </bold>Probiotics compete with the cariogenic oral bacteria like Streptococcus mutans (S. mutans) for carbohydrates resulting in substrate depletion and reduction in the number of S. mutans.<bold>Aim: </bold>The evaluation of topical effect of short-term application of Probiotic formulation on S. mutans counts in plaque of 7-12 years old children with decayed, missing, filled teeth (dmft/DMFT) score 2-5.<bold>Materials and Methods: </bold>A registered randomized clinical trial (Clinical Trials Registry of India/ICMR - CTRI/2019/09/021205) was conducted on 7-12 years medium risk 10 children with dmft/DMFT score 2-5, where an innovative probiotic formulation (prepared from capsule) was applied for 6 consecutive days, on teeth and pre/post plaque samples were evaluated for S. mutans count on mitis salivarius agar.<bold>Results: </bold>There was statistically significant and drastic reduction from 608,200 to 6600 (>90%) in the S. mutans count in plaque after the application of probiotic solution for a short period of time (6 days).<bold>Conclusion: </bold>Short-term application of probiotics can be used as an alternate topical preventive therapy to reduce the count of S. mutans effectively in oral cavity/plaque. Hence, probiotic can be used as topical caries preventive agent.
- Subjects
CAVITY prevention; THERAPEUTIC use of probiotics; RESEARCH; DENTAL plaque; SALIVA; RESEARCH methodology; MEDICAL cooperation; EVALUATION research; COMPARATIVE studies; RANDOMIZED controlled trials; STREPTOCOCCUS mutans
- Publication
Journal of the Indian Society of Pedodontics & Preventive Dentistry, 2021, Vol 39, Issue 3, p279
- ISSN
0970-4388
- Publication type
journal article
- DOI
10.4103/jisppd.jisppd_519_20