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- Title
Cognitive Aging and Rate of Hospitalization in an Urban Population of Older People.
- Authors
Wilson, Robert S.; Rajan, Kumar B.; Barnes, Lisa L.; Hebert, Liesi E.; Mendes de Leon, Carlos F.; Evans, Denis A.
- Abstract
Background. The association of age-related cognitive change with hospitalization is not well understood. Methods. At 3-year intervals for a mean of 8.7 years, 2,273 older residents of a geographically defined urban community underwent cognitive testing from which a global measure was derived. Hospitalization data were obtained from Part A Medicare beneficiary records. The association of level of cognitive function and rate of cognitive decline in each 3-year interval with subsequent rate of hospitalization was assessed using mixed-effects count regression models. Results. There were 9,091 hospitalizations involving 1,810 of the 2,273 individuals in the cohort (79.6%). Rate of hospitalization increased by 9.7% (95% confidence interval [CI]: 7.2, 12.3) with each additional study year; by 32.7% (95% CI: 26.8, 38.0) for each 1 point lower on the global cognitive measure at the beginning of an observation interval; and by 24.3% (95% CI: 16.6, 32.6) for each 1-point decrease in the global cognitive measure during the previous observation period. These associations persisted after adjustment for comorbidities and exclusion of those with a Mini-Mental State Examination score less than 26. Conclusion. Individual differences in trajectories of cognitive aging are associated with subsequent risk of hospitalization.
- Subjects
COGNITIVE ability; HOSPITAL care; URBAN elderly; EPIDEMIOLOGY; PUBLIC health; COGNITIVE testing; COMORBIDITY; MULTILEVEL models
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, Vol 69, Issue 4, p447
- ISSN
1079-5006
- Publication type
Article
- DOI
10.1093/gerona/glt145