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- Title
Carcinosarcoma of the Uterine Corpus a Case Report and Brief Review of the Literature.
- Authors
Georgescu, Tiberiu Augustin; Cirstoiu, Monica; Cirstoiu, Florin Catalin; Costache, Mariana; Lazaroiu, Anca; Dumitru, Adrian; Sajin, Maria
- Abstract
Uterine carcinosarcomas or Malignant Mixed Müllerian Tumors are exceptionally rare and extremely aggressive tumors of the uterine corpus, accounting for less than 1% of all gynecologic malignancies and 2-5% of all uterine malignancies, being responsible for more than 15% of all uterine cancer associated deaths. In this report we present the case of a 66 years old woman with no personal history of gynecologic malignancy, addressing the Department of Obstetrics-Gynecology of the University Emergency Hospital in Bucharest Romania for postmenopausal vaginal bleeding. Ultrasonography and CT scan of the pelvis revealed an endocavitary mass limited to the uterine corpus. As a result, a radical hysterectomy with bilateral salpingo-oophorectomy was carried out under general anesthesia. Microscopic evaluation revealed an admixture of malignant epithelial and mesenchymal components with small foci of clear cell carcinoma and scattered heterologous elements. These features, as well as the gross aspect and immunohistochemical results were consistent with the diagnosis of carcinosarcoma of the uterine corpus. In conclusion, due to the severe outcome and reduced survival rate of these extremely aggressive tumors, we emphasize the importance of awareness, early detection, treatment and proper surgical staging for all females with uterine carcinosarcoma.
- Subjects
UTERINE tumors; CARCINOSARCOMAS; DIAGNOSTIC imaging
- Publication
Medicina Moderna, 2016, Vol 23, Issue 2, p175
- ISSN
1223-0472
- Publication type
Case Study