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- Title
Healing sequence in capped inflamed dental pulps of Rhesus monkeys (<em>Macaca mulatta</em>).
- Authors
Cox, C. F.; Bergenholtz, G.
- Abstract
Buccal class V cavities were prepared in 35 teeth of five adult Rhesus monkeys. Pulpal exposures were left open to the oral microflora for 24 hours. Twenty-eight teeth were pulp-capped with a hard setting Ca(OH)2 medicament and restored with amalgam. Pulpal responses were observed after 24 hours (non-restored), 3, 5, 10 and 14 days. The pulps of teeth capped 3 days previously were dominated by polymorphonuclear leucocytes at the exposure site. Five-day pulp-capped teeth showed clot resolution, areas of necrosis and disintegrating polymorphonuclear leucocytes. Some pulps showed reorganization and stratification of fibroblasts adjacent to the medicament interface. Ten-day pulp-capped teeth showed dentine matrix mineralization directly adjacent to some portion of the medicament interface. Fourteen-day pulp-capped teeth showed complete soft-tissue reorganization and new hard-tissue formation. This study demonstrates that complete pulp healing and new hard-tissue deposition will occur within 14 days, following an acute inflammatory lesion in monkeys.
- Subjects
DENTAL caries; RHESUS monkeys; ORAL microbiology; LEUCOCYTES; FIBROBLASTS; DENTAL amalgams
- Publication
International Endodontic Journal, 1986, Vol 19, Issue 3, p113
- ISSN
0143-2885
- Publication type
Article
- DOI
10.1111/j.1365-2591.1986.tb00463.x