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Gene networks associated with conditional fear in mice identified using a systems genetics approach.
Published in:
BMC Systems Biology, 2011, v. 5, n. 1, p. 43, doi. 10.1186/1752-0509-5-43
By:
- Park, Christopher C.;
- Gale, Greg D.;
- Jong, Simone de;
- Ghazalpour, Anatole;
- Bennett, Brian J.;
- Farber, Charles R.;
- Langfelder, Peter;
- Lin, Andy;
- Khan, Arshad H.;
- Eskin, Eleazar;
- Horvath, Steve;
- Lusis, Aldons J.;
- Ophoff, Roel A.;
- Smith, Desmond J.
Publication type:
Article
The genome-wide expression effects of escitalopram and its relationship to neurogenesis, hippocampal volume, and antidepressant response.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2017, v. 174, n. 4, p. 427, doi. 10.1002/ajmg.b.32532
By:
- Powell, Timothy R.;
- Murphy, Tytus;
- de Jong, Simone;
- Lee, Sang Hyuck;
- Tansey, Katherine E.;
- Hodgson, Karen;
- Uher, Rudolf;
- Price, Jack;
- Thuret, Sandrine;
- Breen, Gerome
Publication type:
Article
TCF4 (e2-2; ITF2): A Schizophrenia-Associated Gene With Pleiotropic Effects on Human Disease.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2013, v. 162B, n. 1, p. 1, doi. 10.1002/ajmg.b.32109
By:
- Navarrete, Katherinne;
- Pedroso, Inti;
- De Jong, Simone;
- Stefansson, Hreinn;
- Steinberg, Stacy;
- Stefansson, Kari;
- Ophoff, Roel A.;
- Schalkwyk, Leonard C.;
- Collier, David A.
Publication type:
Article
Telomere length as a predictor of emotional processing in the brain.
Published in:
Human Brain Mapping, 2019, v. 40, n. 6, p. 1750, doi. 10.1002/hbm.24487
By:
- Powell, Timothy R.;
- De Jong, Simone;
- Breen, Gerome;
- Lewis, Cathryn M.;
- Dima, Danai
Publication type:
Article
BrainGENIE: The Brain Gene Expression and Network Imputation Engine.
Published in:
Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02390-w
By:
- Hess, Jonathan L.;
- Quinn, Thomas P.;
- Zhang, Chunling;
- Hearn, Gentry C.;
- Chen, Samuel;
- Beveridge, Natalie Jane;
- Carr, Vaughan;
- de Jong, Simone;
- Gardiner, Erin;
- Kelly, Brian;
- Kumarasinghe, Nishantha;
- Ophoff, Roel;
- Schall, Ulrich;
- Scott, Rodney;
- Stamova, Boryana;
- Tooney, Paul;
- Kong, Sek Won;
- Cairns, Murray;
- Tsuang, Ming T.;
- Faraone, Stephen V.
Publication type:
Article
Characterization of Genome-Methylome Interactions in 22 Nuclear Pedigrees.
Published in:
PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0099313
By:
- Plongthongkum, Nongluk;
- van Eijk, Kristel R.;
- de Jong, Simone;
- Wang, Tina;
- Sul, Jae Hoon;
- Boks, Marco P. M.;
- Kahn, René S.;
- Fung, Ho-Lim;
- Ophoff, Roel A.;
- Zhang, Kun
Publication type:
Article
Identifying Predictors of Activity Based Anorexia Susceptibility in Diverse Genetic Rodent Populations.
Published in:
PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050453
By:
- Pjetria, Eneda;
- de Haas, Ria;
- de Jong, Simone;
- Gelegen, Cigdem;
- Oppelaar, Hugo;
- Verhagen, Linda A. W.;
- Eijkemans, Marinus J. C.;
- Adan, Roger A.;
- Olivier, Berend;
- Kas, Martien J.
Publication type:
Article
A Gene Co-Expression Network in Whole Blood of Schizophrenia Patients Is Independent of Antipsychotic- Use and Enriched for Brain-Expressed Genes.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039498
By:
- de Jong, Simone;
- Boks, Marco P. M.;
- Fuller, Tova F.;
- Strengman, Eric;
- Janson, Esther;
- de Kovel, Carolien G. F.;
- Ori, Anil P. S.;
- Vi, Nancy;
- Mulder, Flip;
- Blom, Jan Dirk;
- Glenthøj, Birte;
- Schubart, Chris D.;
- Cahn, Wiepke;
- Kahn, René S.;
- Horvath, Steve;
- Ophoff, Roel A.
Publication type:
Article
Hippocampal Gene Expression Analysis Highlights Ly6a/ Sca-1 as Candidate Gene for Previously Mapped Novelty Induced Behaviors in Mice.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020716
By:
- de Jong, Simone;
- Kas, Martien J. H.;
- Kiernan, Jeffrey;
- Malsen, Annetrude G. de Mooij-van;
- Oppelaar, Hugo;
- Janson, Esther;
- Vukobradovic, Igor;
- Farber, Charles R.;
- Stanford, William L.;
- Ophoff, Roel A.
Publication type:
Article
Identification of schizophrenia-associated loci by combining DNA methylation and gene expression data from whole blood.
Published in:
European Journal of Human Genetics, 2015, v. 23, n. 8, p. 1106, doi. 10.1038/ejhg.2014.245
By:
- van Eijk, Kristel R;
- de Jong, Simone;
- Strengman, Eric;
- Buizer-Voskamp, Jacobine E;
- Kahn, René S;
- Boks, Marco P;
- Horvath, Steve;
- Ophoff, Roel A
Publication type:
Article
Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes.
Published in:
European Journal of Human Genetics, 2012, v. 20, n. 9, p. 1004, doi. 10.1038/ejhg.2012.38
By:
- de Jong, Simone;
- van Eijk, Kristel R;
- Zeegers, Dave W L H;
- Strengman, Eric;
- Janson, Esther;
- Veldink, Jan H;
- van den Berg, Leonard H;
- Cahn, Wiepke;
- Kahn, René S;
- Boks, Marco P M;
- Ophoff, Roel A
Publication type:
Article
Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.
Published in:
Translational Psychiatry, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41398-018-0230-7
By:
- Santoro, Marcos Leite;
- Ota, Vanessa;
- de Jong, Simone;
- Noto, Cristiano;
- Spindola, Leticia M.;
- Talarico, Fernanda;
- Gouvea, Eduardo;
- Lee, Sang Hyuck;
- Moretti, Patricia;
- Curtis, Charles;
- Patel, Hamel;
- Newhouse, Stephen;
- Carvalho, Carolina Muniz;
- Gadelha, Ary;
- Cordeiro, Quirino;
- Bressan, Rodrigo Affonseca;
- Belangero, Sintia Iole;
- Breen, Gerome
Publication type:
Article
Seasonal changes in gene expression represent cell-type composition in whole blood.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 10, p. 2721, doi. 10.1093/hmg/ddt665
By:
- De Jong, Simone;
- Neeleman, Marjolein;
- Luykx, Jurjen J.;
- Ten Berg, Maarten J.;
- Strengman, Eric;
- Den Breeijen, Hanneke H.;
- Stijvers, Leon C.;
- Buizer-Voskamp, Jacobine E.;
- Bakker, Steven C.;
- Kahn, René S.;
- Horvath, Steve;
- Van Solinge, Wouter W.;
- Ophoff, Roel A.
Publication type:
Article
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 20, p. 4076, doi. 10.1093/hmg/ddr325
By:
- Steinberg, Stacy;
- de Jong, Simone;
- Andreassen, Ole A.;
- Werge, Thomas;
- Børglum, Anders D.;
- Mors, Ole;
- Mortensen, Preben B.;
- Gustafsson, Omar;
- Costas, Javier;
- Pietiläinen, Olli P. H.;
- Demontis, Ditte;
- Papiol, Sergi;
- Huttenlocher, Johanna;
- Mattheisen, Manuel;
- Breuer, René;
- Vassos, Evangelos;
- Giegling, Ina;
- Fraser, Gillian;
- Walker, Nicholas;
- Tuulio-Henriksson, Annamari
Publication type:
Article
Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
Published in:
Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0155-y
By:
- de Jong, Simone;
- Diniz, Mateus Jose Abdalla;
- Saloma, Andiara;
- Gadelha, Ary;
- Santoro, Marcos L.;
- Ota, Vanessa K.;
- Noto, Cristiano;
- Curtis, Charles;
- Newhouse, Stephen J.;
- Patel, Hamel;
- Hall, Lynsey S.;
- O'Reilly, Paul F.;
- Belangero, Sintia I.;
- Bressan, Rodrigo A.;
- Breen, Gerome
Publication type:
Article
Distinct Effects of Heparin and Interleukin‐4 Functionalization on Macrophage Polarization and In Situ Arterial Tissue Regeneration Using Resorbable Supramolecular Vascular Grafts in Rats.
Published in:
Advanced Healthcare Materials, 2021, v. 10, n. 21, p. 1, doi. 10.1002/adhm.202101103
By:
- Bonito, Valentina;
- Koch, Suzanne E.;
- Krebber, Merle M.;
- Carvajal‐Berrio, Daniel A.;
- Marzi, Julia;
- Duijvelshoff, Renee;
- Lurier, Emily B.;
- Buscone, Serena;
- Dekker, Sylvia;
- de Jong, Simone M. J.;
- Mes, Tristan;
- Vaessen, Koen R. D.;
- Brauchle, Eva M.;
- Bosman, Anton W.;
- Schenke‐Layland, Katja;
- Verhaar, Marianne C.;
- Dankers, Patricia Y. W.;
- Smits, Anthal I. P. M.;
- Bouten, Carlijn V. C.
Publication type:
Article
Serum from Older Adults Increases Apoptosis and Molecular Aging Markers in Human Hippocampal Progenitor Cells.
Published in:
Aging & Disease, 2021, v. 12, n. 8, p. 2151, doi. 10.14336/AD.2021.0409
By:
- de Lucia, Chiara;
- Murphy, Tytus;
- Maruszak, Aleksandra;
- Wright, Paul;
- Powell, Timothy R.;
- Hartopp, Naomi;
- de Jong, Simone;
- O'Sullivan, Michael J.;
- Breen, Gerome;
- Price, Jack;
- Lovestone, Simon;
- Thuret, Sandrine
Publication type:
Article
An Integrative Multi-scale Analysis of the Dynamic DNA Methylation Landscape in Aging.
Published in:
PLoS Genetics, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.pgen.1004996
By:
- Yuan, Tian;
- Jiao, Yinming;
- de Jong, Simone;
- Ophoff, Roel A.;
- Beck, Stephan;
- Teschendorff, Andrew E.
Publication type:
Article
The Alkaline Phosphatase (ALPL) Locus Is Associated with B6 Vitamer Levels in CSF and Plasma.
Published in:
Genes, 2019, v. 10, n. 1, p. 8, doi. 10.3390/genes10010008
By:
- Olde Loohuis, Loes M.;
- Albersen, Monique;
- de Jong, Simone;
- Wu, Timothy;
- Luykx, Jurjen J.;
- Jans, Judith J. M.;
- Verhoeven-Duif, Nanda M.;
- Ophoff, Roel A.
Publication type:
Article
Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner.
Published in:
BMC Genomics, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2164-13-458
By:
- de Jong, Simone;
- Chepelev, Iouri;
- Janson, Esther;
- Strengman, Eric;
- van den Bergv, Leonard H.;
- Veldinkv5, Jan H.;
- Ophoff, Roel A.
Publication type:
Article
Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects.
Published in:
BMC Genomics, 2012, v. 13, n. 1, p. 636, doi. 10.1186/1471-2164-13-636
By:
- van Eijk, Kristel R.;
- de Jong, Simone;
- Boks, Marco P. M.;
- Langeveld, Terry;
- Colas, Fabrice;
- Veldink, Jan H.;
- de Kovel, Carolien G. F.;
- Janson, Esther;
- Strengman, Eric;
- Langfelder, Peter;
- Kahn, Ren� S.;
- van den Berg, Leonard H.;
- Horvath, Steve;
- Ophoff, Roel A.
Publication type:
Article
Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background.
Published in:
BMC Genomics, 2010, v. 11, p. 1, doi. 10.1186/1471-2164-11-20
By:
- De Jong, Simone;
- Fuller, Tova F.;
- Janson, Esther;
- Strengman, Eric;
- Horvath, Steve;
- Kas, Martien J.H.;
- Ophoff, Roel A.
Publication type:
Article
Gene-set analysis based on the pharmacological profiles of drugs to identify repurposing opportunities in schizophrenia.
Published in:
2016
By:
- de Jong, Simone;
- Vidler, Lewis R.;
- Mokrab, Younes;
- Collier, David A.;
- Breen, Gerome
Publication type:
journal article

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