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- Title
Double-blind cross-over trial of oral sodium cromoglycate in patients with irritable bowel syndrome due to food intolerance.
- Authors
Lunardi, C.; Bambara, L. M.; Biasi, D.; Cortina, P.; Peroli, P.; Nicolis, F.; Favari, F.; Pacor, M. L.
- Abstract
Twenty patients with irritable bowel syndrome due to food intolerance were randomized to either oral sodium cromoglycate or placebo in a double-blind cross-over trial. The study consisted of treatment with either sodium cromoglycate or placebo for 8 weeks, followed by the cross-over treatment for 8 further weeks. Patients were allowed to eat the offending foods during the study. Eighteen patients completed the study. Analysis of patients' diary card scores showed a statistically significant difference in favour of sodium cromoglycate. There was a long carry-over effect in the active-placebo order group. Therefore oral sodium cromoglycate seems to be a useful treatment in patients with irritable bowel syndrome and proven food intolerance.
- Subjects
INTESTINAL diseases; IRRITABLE colon; PLACEBOS; BOWEL obstructions; SODIUM content of food; DIARRHEA; PATIENTS
- Publication
Clinical & Experimental Allergy, 1991, Vol 21, Issue 5, p569
- ISSN
0954-7894
- Publication type
Article
- DOI
10.1111/j.1365-2222.1991.tb00848.x