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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson's disease.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37464-2
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- Article
PAT: predictor for structured units and its application for the optimization of target molecules for the generation of synthetic antibodies.
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- BMC Bioinformatics, 2016, p. 1, doi. 10.1186/s12859-016-1001-1
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- Article
PepNN: a deep attention model for the identification of peptide binding sites.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03445-2
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- Article
A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity.
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- Nucleic Acids Research, 2015, v. 43, n. 19, p. 9147, doi. 10.1093/nar/gkv919
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- Article
MUSI: an integrated system for identifying multiple specificity from very large peptide or nucleic acid data sets.
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- Nucleic Acids Research, 2012, v. 40, n. 6, p. e47, doi. 10.1093/nar/gkr1294
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- Article
A universal deep-learning model for zinc finger design enables transcription factor reprogramming.
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- Nature Biotechnology, 2023, v. 41, n. 8, p. 1117, doi. 10.1038/s41587-022-01624-4
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- Article
C2H2 zinc finger proteins greatly expand the human regulatory lexicon.
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- Nature Biotechnology, 2015, v. 33, n. 5, p. 555, doi. 10.1038/nbt.3128
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- Article
Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library.
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- Nature Biotechnology, 2010, v. 28, n. 1, p. 47, doi. 10.1038/nbt.1600
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- Article
Interpreting protein networks with three-dimensional structures.
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- Nature Methods, 2013, v. 10, n. 1, p. 43, doi. 10.1038/nmeth.2300
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- Article
Combining Structural Modeling with Ensemble Machine Learning to Accurately Predict Protein Fold Stability and Binding Affinity Effects upon Mutation.
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- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107353
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- Article
Protein Disorder and Short Conserved Motifs in Disordered Regions Are Enriched near the Cytoplasmic Side of Single-Pass Transmembrane Proteins.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044389
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- Article
Computational structural analysis of protein interactions and networks.
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- Proteomics, 2012, v. 12, n. 10, p. 1697, doi. 10.1002/pmic.201100597
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- Article
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains.
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- BMC Bioinformatics, 2010, v. 11, p. 243, doi. 10.1186/1471-2105-11-243
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- Article
Large‐scale survey and database of high affinity ligands for peptide recognition modules.
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- Molecular Systems Biology, 2020, v. 16, n. 12, p. 1, doi. 10.15252/msb.20199310
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- Article
The multiple-specificity landscape of modular peptide recognition domains.
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- Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.18
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- Article
Chaperonin activity modulates codon adaptation.
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- 2010
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- Publication type:
- Opinion
The role of disorder in interaction networks: a structural analysis.
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- Molecular Systems Biology, 2008, v. 4, n. 1, p. 1, doi. 10.1038/msb.2008.16
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- Article
Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome.
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- FEBS Journal, 2017, v. 284, n. 3, p. 485, doi. 10.1111/febs.13995
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- Article
Distinct Types of Disorder in the Human Proteome: Functional Implications for Alternative Splicing.
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- PLoS Computational Biology, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pcbi.1003030
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- Article
Network Evolution: Rewiring and Signatures of Conservation in Signaling.
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- PLoS Computational Biology, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pcbi.1002411
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- Article
Measuring the Evolutionary Rewiring of Biological Networks.
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- PLoS Computational Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1371/journal.pcbi.1001050
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- Article
The Importance of Bottlenecks in Protein Networks: Correlation with Gene Essentiality and Expression Dynamics.
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- PLoS Computational Biology, 2007, v. 3, n. 4, p. e59, doi. 10.1371/journal.pcbi.0030059
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- Article
Evolution of biological interaction networks: from models to real data.
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- Genome Biology, 2011, v. 12, n. 12, p. 235, doi. 10.1186/gb-2011-12-12-235
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- Article
Bringing order to protein disorder through comparative genomics and genetic interactions.
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- Genome Biology, 2011, v. 12, n. 2, p. 1, doi. 10.1186/gb-2011-12-2-r14
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- Article
Gate-based quantum computing for protein design.
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- PLoS Computational Biology, 2023, v. 19, n. 4, p. 1, doi. 10.1371/journal.pcbi.1011033
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- Article
Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins.
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- PLoS Biology, 2009, v. 7, n. 10, p. 1, doi. 10.1371/journal.pbio.1000218
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- Article
An integrated system for studying residue coevolution in proteins.
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- Bioinformatics, 2008, v. 24, n. 2, p. 290, doi. 10.1093/bioinformatics/btm584
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- Article
The tYNA platform for comparative interactomics: a web tool for managing, comparing and mining multiple networks.
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- Bioinformatics, 2007, v. 23, n. 8, p. 1048, doi. 10.1093/bioinformatics/btm099
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- Article
The tYNA platform for comparative interactomics: a web tool for managing, comparing and mining multiple networks.
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- Bioinformatics, 2006, v. 22, n. 23, p. 2968, doi. 10.1093/bioinformatics/btl488
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- Article
The geometric influence on the Cys<sub>2</sub>His<sub>2</sub> zinc finger domain and functional plasticity.
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- Nucleic Acids Research, 2020, v. 48, n. 11, p. 6382, doi. 10.1093/nar/gkaa291
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- Article
The Chemical Fluctuation Theorem governing gene expression.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02737-0
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- Publication type:
- Article
Non-base-contacting residues enable kaleidoscopic evolution of metazoan C2H2 zinc finger DNA binding.
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- Genome Biology, 2017, v. 18, n. 1, p. 1, doi. 10.1186/s13059-017-1287-y
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- Article
Proteomic peptide phage display uncovers novel interactions of the PDZ1-2 supramodule of syntenin.
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- FEBS Letters, 2016, v. 590, n. 1, p. 3, doi. 10.1002/1873-3468.12037
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- Article
Elucidation of the binding preferences of peptide recognition modules: SH3 and PDZ domains
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- FEBS Letters, 2012, v. 586, n. 17, p. 2631, doi. 10.1016/j.febslet.2012.05.043
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- Article
High-Resolution Copy-Number Variation Map Reflects Human Olfactory Receptor Diversity and Evolution.
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- PLoS Genetics, 2008, v. 4, n. 11, p. 1, doi. 10.1371/journal.pgen.1000249
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- Article
Predicting changes in protein stability caused by mutation using sequence‐and structure‐based methods in a CAGI5 blind challenge.
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- Human Mutation, 2019, v. 40, n. 9, p. 1414, doi. 10.1002/humu.23852
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- Article
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge.
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- Human Mutation, 2019, v. 40, n. 9, p. 1392, doi. 10.1002/humu.23843
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- Article
GDockScore: a graph-based protein–protein docking scoring function.
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- Bioinformatics Advances, 2023, v. 3, n. 1, p. 1, doi. 10.1093/bioadv/vbad072
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- Article
Rapid and accurate structure‐based therapeutic peptide design using GPU accelerated thermodynamic integration.
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- Proteins, 2019, v. 87, n. 3, p. 236, doi. 10.1002/prot.25644
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- Article
Motif mediated protein-protein interactions as drug targets.
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- Cell Communication & Signaling, 2016, v. 14, p. 1, doi. 10.1186/s12964-016-0131-4
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- Article
ELASPIC web-server: proteome-wide structure-based prediction of mutation effects on protein stability and binding affinity.
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- Bioinformatics, 2016, v. 32, n. 10, p. 1589, doi. 10.1093/bioinformatics/btw031
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- Article
JBASE: Joint Bayesian Analysis of Subphenotypes and Epistasis.
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- Bioinformatics, 2016, v. 32, n. 2, p. 203, doi. 10.1093/bioinformatics/btv504
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- Article
Rewiring of Transcriptional Regulatory Networks: Hierarchy, Rather than Connectivity, Better Reflects the Importance of Regulators.
- Published in:
- Science Signaling, 2010, v. 3, n. 146, p. 1, doi. 10.1126/scisignal.2001014
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- Article
Deciphering Protein Kinase Specificity Through Large-Scale Analysis of Yeast Phosphorylation Site Motifs.
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- Science Signaling, 2010, v. 3, n. 109, p. 1, doi. 10.1126/scisignal.2000482
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- Article
Understanding Modularity in Molecular Networks Requires Dynamics.
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- Science Signaling, 2009, v. 2, n. 81, p. 1, doi. 10.1126/scisignal.281pe44
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- Article
A computational approach for designing D-proteins with non-canonical amino acid optimised binding affinity.
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- PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187524
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- Article
Data driven flexible backbone protein design.
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- PLoS Computational Biology, 2017, v. 13, n. 8, p. 1, doi. 10.1371/journal.pcbi.1005722
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- Article