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- Title
Increased expression of aquaporin-4 in brain tissue of amygdala-kindled rats.
- Authors
Yinghui Chen; Yongbo Zhao
- Abstract
The article presents a study which explained the role of aquaporin-4 in the development of brain edema due to recurring seizures in epilepsy.The researchers set up a rat model of epilepsy by repeated electrical stimulation of the amygdala (kindling). They found that AQP-4 was over expressed in the brain of amygdala kindled rats. They concluded that repeated seizures affect water homeostasis in the brain.
- Subjects
AQUAPORINS; CEREBRAL edema; EPILEPSY; ELECTRIC stimulation; AMYGDALOID body; WATER-electrolyte balance (Physiology)
- Publication
Neural Regeneration Research, 2011, Vol 6, Issue 32, p2495
- ISSN
1673-5374
- Publication type
Article
- DOI
10.3969/j.issn.1673-5374.2011.32.003