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- Title
Bacterial Diarrhea in HIV-Infected Patients: Why Clostridium difficile, and Why Now?
- Authors
Sivapalasingam, Sumathi; Blaser, Martin J.
- Abstract
This article focuses on Clostridium difficile associated diarrhea in HIV-infected patients. For patients with clinical AIDS who are exposed to C. difficile, the absence of antitoxin A antibodies could be important in pathogenesis. Patients with immunologic AIDS are less likely to receive anti-infectives or to be hospitalized, reducing the risk of exposure. C. difficile associated diarrhea and its most severe form, pseudomembranous colitis, are mediated by exotoxins A and B of pathogenic C. difficile strains.
- Subjects
DIARRHEA; CLOSTRIDIOIDES difficile; HIV-positive persons; ANTITOXINS; IMMUNOGLOBULINS; TOXINS
- Publication
Clinical Infectious Diseases, 2005, Vol 41, Issue 11, p1628
- ISSN
1058-4838
- Publication type
Editorial
- DOI
10.1086/498037