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- Title
Manisa ili hepatit A seronegatifliği ve sosyal belirleyicilerle ilişkisi, 2014.
- Authors
GÖRGEL-KAHRAMAN, Hilal; ALPAY-ÖZBEK, Özgen; EMEK, Mestan; ATASOYLU, Gonca; SEKRETER, Özgür; ÜNAL, Belgin
- Abstract
Objective: The aim of this cross-sectional study is to investigate the relationship between hepatitis A seronegativity and some social determinants above 2 years of age in Manisa province, in 2014. Methods: The study was carried out using the data and obtained from the study titled 'Determining the Seroprevalence of Some Vaccine-Preventable Diseases in Manisa'. The dependent variable was hepatitis A seronegativity; gender, age group, educational level, occupational class, annual income per capita, perceived income status, household density (number of people per room) and childhood place of residence were the independent variables. Serum samples were analyzed for total anti-HAV positivity with electrochemiluminescence immunoassay method by a Roche-Cobas e 411 (Roche Diagnostics GmbH, Mannheim, Germany) analyzor (Roche Cobas Elecsys) and compatible kits. The relationship between dependent and independent variables were examined by using chi-square test for categorical variables. The adjusted odds ratios (OR) and 95% confidence intervals (CI) for each variable were calculated by logistic regression method. Results: In this study, it was analyzed data obtained from 1223 person. It was detected hepatitis A seronegativity as 24.4%. The highest age groups of hepatitis A seronegativity were 2-9, 10-19 and 20-29, with the percents of 78.5%, 65.8% and 31.3% respectively. Seronegativity percentages range from 0.0% to 5.5% in groups over 30 years of age. While Köprübaşı district (8.30%) had the lowest hepatitis A seronegativity Kırkağaç (34.6%) had the highest. When it was evaluated the association between social determinants and hepatitis A seronegativity; it was found that having an equivalent of annual income per capita equal or lower than 3265 TL had a protective effect on hepatitis A seronegativity (OR: 0.61, 95% CI: 0.42-0.90). According to the density of the households, it was found that those who had more than one person had a protective effect on hepatitis A seronegativity (OR: 0.48, 95% CI: 0.32-0.71). There was no significant association between hepatitis A seronegativity and gender, place of childhood, place of residence, educational status, occupational status, perceived income level and toilet location of the dwelling (p> 0.05). Conclusion: Hepatitis A vaccination should be performed because of high contagiousness during childhood and increasing mortality and morbidity with aging. Districts with high hepatitis A seronegativity, families with low-income and households with high density must be prioritised for immunization and health education services.
- Subjects
MANNHEIM (Germany); GERMANY; HEPATITIS A vaccines; AGE groups; HEALTH education; CHI-squared test; PER capita
- Publication
Turkish Bulletin of Hygiene & Experimental Biology / Türk Hijyen ve Deneysel Biyoloji, 2019, Vol 76, Issue 2, p131
- ISSN
0377-9777
- Publication type
Article
- DOI
10.5505/TurkHijyen.2018.05826