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- Title
Concurrent Gastric and Pulmonary Mucosa-Associated Lymphoid Tissue Lymphomas with Pre-Existing Intrinsic Chronic Inflammation: A Case Report and a Review of the Literature.
- Authors
Sooyeon Oh; Nayoung Kim; Dong Hyun Oh; Soo-Mee Bang; Yoon Jin Choi; Ju Yub Lee; Kyung Won Lee; Ho Il Yoon; Hee Chul Yang; Jin Ho Paik; Dong Ho Lee; Hyun Chae Jung
- Abstract
Herein, we report a rare case of concurrent gastric and pulmonary mucosa-associated lymphoid tissue (MALT) lymphomas. A 65-year-old man who had been diagnosed with Helicobacter pylori-positive gastric MALT lymphoma received eradication therapy and achieved complete remission. During follow-up, he developed de novo pulmonary MALT lymphoma as a sequela of pulmonary tuberculosis, accompanied by recurrent gastric MALT lymphoma. Polymerase chain reaction (PCR) products of the CDR3 region of the immunoglobulin heavy chain gene showed an overall polyclonal pattern with bands at 400 base pairs (bp) and 200 bp predominant in the pulmonary tissue, as well as two distinctive bands in the gastric tissue at 400 bp and 200 bp. This case suggests that multiorgan lymphomas are more likely to be independent from each other when they are far apart, involve different organ systems, and have independent precipitating factors.
- Subjects
MUCOSA-associated lymphoid tissue lymphoma; HELICOBACTER pylori infections; LYMPHOMA treatment; SPONTANEOUS cancer regression; IMMUNOGLOBULINS; POLYMERASE chain reaction
- Publication
Gut & Liver, 2015, Vol 9, Issue 3, p424
- ISSN
1976-2283
- Publication type
Case Study
- DOI
10.5009/gnl14072