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- Title
Natural Saline-Flush Is Sufficient to Maintain Patency of Immobilized-Urokinase Double-Lumen Catheter Used to Provide Temporary Blood Access for Hemodialysis.
- Authors
Kaneko, Yoshikatsu; Iwano, Masako; Yoshida, Hitomi; Kosuge, Miyoko; Ito, Sanae; Narita, Ichiei; Gejyo, Fumitake; Suzuki, Masashi
- Abstract
Background: Thrombotic occlusion is a frequent complication of central venous catheters used to provide temporary blood access on hemodialysis therapy. Heparin-lock is conventionally used to maintain patency of the catheter, but the necessity of heparin-lock has not been determined yet. Methods: After the immobilized-urokinase double-lumen central venous catheter was inserted into 48 Japanese hemodialysis patients, 22 patients randomized to the heparin group received a 20-ml saline-flush, followed by 2 ml of 1,000 U/ml heparin-lock, and 26 patients randomized to the saline group received only the 20-ml saline-flush once a day for each lumen. Results: Thrombotic occlusion was observed in only 1 out of 22 patients in the heparin group and 1 out of 26 patients in the saline group. No significant difference of the catheter survival was observed between the two groups (p = 0.8599). Conclusions: Natural saline-flush is sufficient for maintaining the patency of an immobilized-urokinase double-lumen central venous catheter. Copyright © 2004 S. Karger AG, Basel
- Publication
Blood Purification, 2004, Vol 22, Issue 5, p473
- ISSN
0253-5068
- Publication type
Article
- DOI
10.1159/000081811