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- Title
Synthesis, Transformations, and Physicochemical Properties of 3-(4′-Methylphenyl)-8-Methylxanthine Derivatives.
- Authors
Aleksandrova, E.; Levich, S.; Romanenko, N.; Shkoda, A.; Mikhal′chenko, E.
- Abstract
A preparative method for producing of 3-(4′-methylphenyl)-8-methylxanthine, its 7-substituted derivatives, 3-(4′-methylphenyl)-8-methylxanthinyl-7-acetic acid, its ester, amide, hydrazide, ylidenehydrazides, and N-phenylhydrazinocarbothiamide was developed. The structure of the cyclization product of the last, 3-(4′-methylphenyl)-7-[2-(4″-phenyl-5″-thio-4″ H-[1″,2″,4″]triazol-3″-yl)methyl]xanthine, was confirmed by elemental analysis and PMR spectroscopy.
- Subjects
CHEMICAL synthesis; METHYLPHENIDATE; METHYLXANTHINES; HYDRAZIDES; RING formation (Chemistry); NUCLEAR magnetic resonance
- Publication
Chemistry of Natural Compounds, 2014, Vol 49, Issue 6, p1105
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-014-0830-2