We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
EXTENDED-SPECTRUM BETA-LACTAMASE PRODUCING GRAM NEGATIVE BACTERIA IN IRAN: A REVIEW.
- Authors
Leylabadlo, Hamed Ebrahimzadeh; Pourlak, Tala; bialvaei, Abed Zahedi; Aghazadeh, Mohammad; Asgharzadeh, Mohammad; Kafil, Hossein Samadi
- Abstract
Background: The emergence and spread of extended spectrum â-lactamase (ESBL)-producing Gram- negative bacteria (GNB), particularly in Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa, have increased all over the world. ESBLs are characterized by their ability to hydrolyze â-lactams, early cephalosporins, oxyimino-thiazolyl cephalosporins, and monobactams, but not cephamycins or carbapenems. The rate of nosocomial infections caused by ESBL-producing GNB in Asia Pacific has increased and several studies have identified their prevalence in the region. The aim of this study is to review the prevalence of ESBL-producing GNB in the West Asia and the Middle East with a particular focus on Iran. Materials and Methods: The available evidence from various studies (Microbia and clinical studies, retrieved from the PubMed, and Scopus databases) regarding the ESBL producing Gram negative bacteria in Iran were evaluated. Results: In almost all parts of the country, high resistance has been observed, especially in the central part of Iran. Up to 89.8% Escherichia coli, 72.1% Klebsiella pneumonia, 84.2% Acinetobacter baumannii, and 83.8% Pseudomonas aeruginosa isolates are ESBL positive. Conclusion: The present study showed the increasing prevalence of ESBLs in different regions of Iran, which could be useful to strategic policy towards reducing reduce their prevalence.
- Subjects
IRAN; GRAM-negative bacteria; ENTEROBACTER cloacae; ACINETOBACTER baumannii; KLEBSIELLA pneumoniae; PSEUDOMONAS aeruginosa; NOSOCOMIAL infections
- Publication
African Journal of Infectious Diseases, 2017, Vol 11, Issue 2, p39
- ISSN
2006-0165
- Publication type
Article
- DOI
10.21010/ajid.v11i2.6