We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Profiles of Extrapulmonary Nontuberculous Mycobacteria Infections and Predictors for Species: A Multicenter Retrospective Study.
- Authors
Kim, Jung Ho; Jung, In Young; Song, Je Eun; Kim, Eun Jin; Kim, Jun Hyoung; Lee, Woon Ji; Seong, Hye; Ahn, Jin Young; Jeong, Su Jin; Ku, Nam Su; Choi, Jun Yong; Yeom, Joon-Sup; Song, Young Goo
- Abstract
Extrapulmonary nontuberculous mycobacteria (NTM) infections contribute to morbidity and mortality worldwide. However, studies about extrapulmonary NTM infections have been limited. Therefore, we aim to describe the diversity of extrapulmonary NTM infections and identify predictors for species. Information regarding diversity of NTM isolates, antimicrobial susceptibility testing, treatment regimens, and outcomes were collected from four tertiary care centers in South Korea. Comparisons were made between patients with rapidly growing mycobacteria (RGM) and slowly growing mycobacteria (SGM) infections. A total of 117 patients (46 males vs. 71 females) were included. Skin and soft tissue infections (SSTIs) predominated (34.2%), followed by bone and joint infections (28.2%). In SSTIs, RGM species were predominantly identified (26/28, 92.9%), whereas SGM species were mainly identified in bone and joint infections (18/26, 69.2%), and the difference of isolated sites was verified by a post hoc test (p < 0.001). Multivariable regression analysis revealed that male sex (vs. female sex; OR 5.30, CI 1.35–24.26, p = 0.020) and bone and joint infections (vs. SSTIs; OR 18.10, CI 3.28–157.07, p = 0.002) were predictors of SGM infections, whereas the opposite was observed for RGM infections. Bone and joint infections and male sex were predictors for SGM infections, whereas SSTIs and female sex were predictors for RGM infections.
- Subjects
SOUTH Korea; SOFT tissue infections; MYCOBACTERIA; JOINTS (Anatomy); MICROBIAL sensitivity tests; JOINT infections; INFECTION
- Publication
Pathogens, 2020, Vol 9, Issue 11, p949
- ISSN
2076-0817
- Publication type
Article
- DOI
10.3390/pathogens9110949