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- Title
Deglycosylated bleomycin has the antitumor activity of bleomycin without pulmonary toxicity.
- Authors
Burgy, Olivier; Wettstein, Guillaume; Bellaye, Pierre S.; Decologne, Nathalie; Racoeur, Cindy; Goirand, Françoise; Beltramo, Guillaume; Hernandez, Jean-François; Kenani, Abderraouf; Camus, Philippe; Bettaieb, Ali; Garrido, Carmen; Bonniaud, Philippe
- Abstract
The article discusses the study on the anticancer activity and lung toxicity of deglycosylated bleomycin (BLM). The study reportedly involved a comparison of the anticancer activity and lung toxicity of deglyco-BLM and BLM in mice. The results revealed that deglycosylated BLM has antitumor activity without pulmonary toxicity.
- Subjects
BLEOMYCIN; CANCER treatment; LABORATORY mice; DEGLYCOSYLATION; ANTINEOPLASTIC antibiotics
- Publication
Science Translational Medicine, 2016, Vol 8, Issue 326, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aad7785