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Design of Optical‐Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease‐Tissue Extracts.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 43, p. 19305, doi. 10.1002/ange.202006719
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- Publication type:
- Article
Emerging principles in protease-based drug discovery.
- Published in:
- 2010
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- Publication type:
- journal article
Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18676-w
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- Publication type:
- Article
Reynoutria Rhizomes as a Natural Source of SARS-CoV-2 Mpro Inhibitors–Molecular Docking and In Vitro Study.
- Published in:
- Pharmaceuticals (14248247), 2021, v. 14, n. 8, p. 742, doi. 10.3390/ph14080742
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- Publication type:
- Article
Betulin and Its Derivatives Reduce Inflammation and COX-2 Activity in Macrophages.
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- Inflammation, 2023, v. 46, n. 2, p. 573, doi. 10.1007/s10753-022-01756-4
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- Publication type:
- Article
Structural Determinants of Substrate Specificity of SplF Protease from Staphylococcus aureus.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2220, doi. 10.3390/ijms22042220
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- Publication type:
- Article
Mapping the substrate specificity of the Plasmodium M1 and M17 aminopeptidases.
- Published in:
- Biochemical Journal, 2021, v. 478, n. 13, p. 2697, doi. 10.1042/BCJ20210172
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- Publication type:
- Article
Evaluation of the effects of phosphorylation of synthetic peptide substrates on their cleavage by caspase-3 and -7.
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- Biochemical Journal, 2021, v. 478, n. 12, p. 2233, doi. 10.1042/BCJ20210255
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- Publication type:
- Article
X-ray crystal structure and specificity of the Toxoplasma gondii ME49 TgAPN2.
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- Biochemical Journal, 2020, v. 477, n. 19, p. 3819, doi. 10.1042/BCJ20200569
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- Publication type:
- Article
Structure and substrate fingerprint of aminopeptidase P from Plasmodium falciparum.
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- Biochemical Journal, 2016, v. 473, n. 19, p. 3189, doi. 10.1042/BCJ20160550
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- Publication type:
- Article
SARS hCoV papain-like protease is a unique Lys<sup>48</sup> linkage-specific di-distributive deubiquitinating enzyme.
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- Biochemical Journal, 2015, v. 468, n. 2, p. 215, doi. 10.1042/BJ20141170
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- Publication type:
- Article
The Strategies to Support the COVID-19 Vaccination with Evidence-Based Communication and Tackling Misinformation.
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- Vaccines, 2021, v. 9, n. 2, p. 109, doi. 10.3390/vaccines9020109
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- Publication type:
- Article
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PL<sup>pro</sup> and M<sup>pro</sup> proteases, and nsp14 guanine N7-methyltransferase.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35907-w
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- Publication type:
- Article
Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families.
- Published in:
- Scientific Reports, 2017, p. 43135, doi. 10.1038/srep43135
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- Publication type:
- Article
Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132818
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- Publication type:
- Article
Fingerprinting the Substrate Specificity of M1 and M17 Aminopeptidases of Human Malaria, Plasmodium falciparum.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031938
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- Publication type:
- Article
A remarkable activity of human leukotriene A hydrolase (LTA4H) toward unnatural amino acids.
- Published in:
- Amino Acids, 2014, v. 46, n. 5, p. 1313, doi. 10.1007/s00726-014-1694-2
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- Publication type:
- Article
Unnatural amino acids increase activity and specificity of synthetic substrates for human and malarial cathepsin C.
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- Amino Acids, 2014, v. 46, n. 4, p. 931, doi. 10.1007/s00726-013-1654-2
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- Publication type:
- Article
Molecular determinants involved in activation of caspase 7.
- Published in:
- Bioscience Reports, 2011, v. 31, n. 4, p. 283, doi. 10.1042/BSR20100111
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- Publication type:
- Article
High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated Neutrophils.
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- Biological Procedures Online, 2020, v. 22, n. 1, p. 1, doi. 10.1186/s12575-020-00118-4
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- Publication type:
- Article
Differential specificity of SARS‐CoV‐2 main protease variants on peptide versus protein‐based substrates.
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- FEBS Journal, 2024, v. 291, n. 1, p. 61, doi. 10.1111/febs.16970
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- Publication type:
- Article
Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide‐based substrates and covalent inhibitors.
- Published in:
- FEBS Journal, 2019, v. 286, n. 20, p. 3998, doi. 10.1111/febs.14953
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- Publication type:
- Article
Amino acid variants of SARS-CoV-2 papain-like protease have impact on drug binding.
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- PLoS Computational Biology, 2022, v. 18, n. 11, p. 1, doi. 10.1371/journal.pcbi.1010667
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- Publication type:
- Article
Thermoprotection by a cell membrane–localized metacaspase in a green alga.
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- Plant Cell, 2024, v. 36, n. 3, p. 665, doi. 10.1093/plcell/koad289
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- Publication type:
- Article
Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49840-4
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- Publication type:
- Article
Emerging challenges in the design of selective substrates, inhibitors and activity-based probes for indistinguishable proteases.
- Published in:
- FEBS Journal, 2017, v. 284, n. 10, p. 1518, doi. 10.1111/febs.14001
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- Publication type:
- Article
Mapping the substrate-binding subsite specificity of a Porphyromonas gingivalis Tpr peptidase.
- Published in:
- Acta Biochimica Polonica, 2023, v. 70, n. 4, p. 963, doi. 10.18388/abp.2020_6604
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- Publication type:
- Article
WALNE ZGROMADZENIA CZŁONKÓW W ODDZIAŁACH POLSKIEGO TOWARZYSTWA BIOCHEMICZN.
- Published in:
- Advances in Biochemistry / Postepy Biochemii, 2022, v. 68, n. 4, p. 444
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- Publication type:
- Article
Design of Optical‐Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease‐Tissue Extracts.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 43, p. 19143, doi. 10.1002/anie.202006719
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- Publication type:
- Article
An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing.
- Published in:
- Microbial Cell Factories, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12934-020-01392-3
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- Publication type:
- Article
SUMO-mediated regulation of NLRP3 modulates inflammasome activity.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05321-2
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- Publication type:
- Article
Applications of Unnatural Amino Acids in Protease Probes.
- Published in:
- Chemistry - An Asian Journal, 2019, v. 14, n. 23, p. 4103, doi. 10.1002/asia.201901152
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- Publication type:
- Article
Trojan Horse Strategies Used by Pathogens to Influence the Small Ubiquitin-Like Modifier (SUMO) System of Host Eukaryotic Cells.
- Published in:
- Journal of Innate Immunity, 2012, v. 4, n. 2, p. 159, doi. 10.1159/000335027
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- Publication type:
- Article
Stereoselective synthesis of 1-aminoalkanephosphonic acids with two chiral centers and their activity towards leucine aminopeptidase.
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- Chirality, 2003, v. 15, n. S1, p. S104, doi. 10.1002/chir.10261
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- Publication type:
- Article
Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines.
- Published in:
- Molecules, 2009, v. 14, n. 4, p. 1639, doi. 10.3390/molecules14041639
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- Publication type:
- Article
Determination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34476-7
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- Publication type:
- Article
DeSUMOylating enzymes—SENPs.
- Published in:
- IUBMB Life, 2008, v. 60, n. 11, p. 734, doi. 10.1002/iub.113
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- Publication type:
- Article
Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity.
- Published in:
- Nature Protocols, 2017, v. 12, n. 10, p. 2189, doi. 10.1038/nprot.2017.091
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- Publication type:
- Article
Small molecules not direct activators of caspases.
- Published in:
- 2007
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- Publication type:
- Letter
Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45).
- Published in:
- Cancer Cell International, 2017, v. 17, p. 1, doi. 10.1186/s12935-016-0369-3
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- Publication type:
- Article
Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits.
- Published in:
- Biological Chemistry, 2023, v. 404, n. 2/3, p. 221, doi. 10.1515/hsz-2022-0261
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- Publication type:
- Article
Human 20S proteasome activity towards fluorogenic peptides of various chain lengths.
- Published in:
- Biological Chemistry, 2016, v. 397, n. 9, p. 921, doi. 10.1515/hsz-2016-0176
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- Publication type:
- Article
Recent advances and concepts in substrate specificity determination of proteases using tailored libraries of fluorogenic substrates with unnatural amino acids.
- Published in:
- Biological Chemistry, 2015, v. 396, n. 4, p. 329, doi. 10.1515/hsz-2014-0315
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- Publication type:
- Article
Profiling of coronaviral M<sup>pro</sup> and enteroviral 3C<sup>pro</sup> specificity provides a framework for the development of broad‐spectrum antiviral compounds.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 9, p. 1, doi. 10.1002/pro.5139
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- Publication type:
- Article
Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 8, p. 1, doi. 10.1002/pro.5110
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- Publication type:
- Article
The Staphylococcus aureus leucine aminopeptidase is localized to the bacterial cytosol and demonstrates a broad substrate range that extends beyond leucine.
- Published in:
- Biological Chemistry, 2013, v. 394, n. 6, p. 791, doi. 10.1515/hsz-2012-0308
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- Publication type:
- Article
Gingipain aminopeptidase activities in Porphyromonas gingivalis.
- Published in:
- Biological Chemistry, 2012, v. 393, n. 12, p. 1471, doi. 10.1515/hsz-2012-0222
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- Publication type:
- Article
Current and prospective applications of non-proteinogenic amino acids in profiling of proteases substrate specificity.
- Published in:
- Biological Chemistry, 2012, v. 393, n. 9, p. 843, doi. 10.1515/hsz-2012-0167
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- Publication type:
- Article