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Phase I trial of the TNF-α inhibitor certolizumab plus chemotherapy in stage IV lung adenocarcinomas.
Published in:
Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-33719-6
By:
- Paik, Paul K.;
- Luo, Jia;
- Ai, Ni;
- Kim, Rachel;
- Ahn, Linda;
- Biswas, Anup;
- Coker, Courtney;
- Ma, Wanchao;
- Wong, Phillip;
- Buonocore, Darren J.;
- Lai, W. Victoria;
- Chaft, Jamie E.;
- Acharyya, Swarnali;
- Massagué, Joan;
- Kris, Mark G.
Publication type:
Article
Tepotinib in patients with NSCLC harbouring MET exon 14 skipping: Japanese subset analysis from the Phase II VISION study.
Published in:
Japanese Journal of Clinical Oncology, 2021, v. 51, n. 8, p. 1261, doi. 10.1093/jjco/hyab072
By:
- Sakai, Hiroshi;
- Morise, Masahiro;
- Kato, Terufumi;
- Matsumoto, Shingo;
- Sakamoto, Tomohiro;
- Kumagai, Toru;
- Tokito, Takaaki;
- Atagi, Shinji;
- Kozuki, Toshiyuki;
- Tanaka, Hiroshi;
- Chikamori, Kenichi;
- Shinagawa, Naofumi;
- Takeoka, Hiroaki;
- Bruns, Rolf;
- Straub, Josef;
- Schumacher, Karl Maria;
- Paik, Paul K
Publication type:
Article
Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.
Published in:
Nature Medicine, 2014, v. 20, n. 9, p. 1027, doi. 10.1038/nm.3667
By:
- Lovly, Christine M;
- McDonald, Nerina T;
- Chen, Heidi;
- Ortiz-Cuaran, Sandra;
- Heukamp, Lukas C;
- Yan, Yingjun;
- Florin, Alexandra;
- Ozretić, Luka;
- Lim, Diana;
- Wang, Lu;
- Chen, Zhao;
- Chen, Xi;
- Lu, Pengcheng;
- Paik, Paul K;
- Shen, Ronglai;
- Jin, Hailing;
- Buettner, Reinhard;
- Ansén, Sascha;
- Perner, Sven;
- Brockmann, Michael
Publication type:
Article
Phase 1 Trial of MLN0128 (Sapanisertib) and CB-839 HCl (Telaglenastat) in Patients With Advanced NSCLC (NCI 10327): Rationale and Study Design.
Published in:
2021
By:
- Riess, Jonathan W.;
- Frankel, Paul;
- Shackelford, David;
- Dunphy, Mark;
- Badawi, Ramsey D.;
- Nardo, Lorenzo;
- Cherry, Simon R.;
- Lanza, Ian;
- Reid, Joel;
- Gonsalves, Wilson I.;
- Kunos, Charles;
- Gandara, David R.;
- Lara, Primo N.;
- Newman, Edward;
- Paik, Paul K.
Publication type:
journal article
Identifying the Optimal Radiation Dose in Locally Advanced Non-Small-cell Lung Cancer Treated With Definitive Radiotherapy Without Concurrent Chemotherapy.
Published in:
2018
By:
- Sonnick, Mark A.;
- Oro, Federica;
- Yan, Bernice;
- Desai, Anish;
- Wu, Abraham J.;
- Shi, Weiji;
- Zhigang Zhang;
- Gelblum, Daphna Y.;
- Paik, Paul K.;
- Yorke, Ellen D.;
- Rosenzweig, Kenneth E.;
- Chaft, Jamie E.;
- Rimner, Andreas;
- Zhang, Zhigang
Publication type:
journal article
Successful Use of Afatinib After Erlotinib-induced Pneumonitis in a Patient With Epidermal Growth Factor Receptor-mutant Lung Cancer.
Published in:
2017
By:
- Jakubowski, Christopher D;
- Plodkowski, Andrew J;
- Chang, Jason C;
- Rekhtman, Natasha;
- Iqbal, Afsheen;
- Paik, Paul K;
- Yu, Helena A
Publication type:
journal article
Regulatory B Cell Function Is Suppressed by Smoking and Obesity in H. pylori-Infected Subjects and Is Correlated with Elevated Risk of Gastric Cancer.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0134591
By:
- Li, Guanggang;
- Wulan, Hasi;
- Song, Zongchang;
- Paik, Paul A.;
- Tsao, Ming L.;
- Goodman, Gary M.;
- MacEachern, Paul T.;
- Downey, Robert S.;
- Jankowska, Anna J.;
- Rabinowitz, Yaron M.;
- Learch, Thomas B.;
- Song, David Z.;
- Yuan, Ji J.;
- Zheng, Shihang;
- Zheng, Zhendong
Publication type:
Article
Breast adipose tissue‐derived extracellular vesicles from obese women alter tumor cell metabolism.
Published in:
EMBO Reports, 2023, v. 24, n. 12, p. 1, doi. 10.15252/embr.202357339
By:
- Liu, Shuchen;
- Benito‐Martin, Alberto;
- Pelissier Vatter, Fanny A;
- Hanif, Sarah Z;
- Liu, Catherine;
- Bhardwaj, Priya;
- Sethupathy, Praveen;
- Farghli, Alaa R;
- Piloco, Phoebe;
- Paik, Paul;
- Mushannen, Malik;
- Dong, Xue;
- Otterburn, David M;
- Cohen, Leslie;
- Bareja, Rohan;
- Krumsiek, Jan;
- Cohen‐Gould, Leona;
- Calto, Samuel;
- Spector, Jason A;
- Elemento, Olivier
Publication type:
Article
Diagnosis, testing, treatment, and outcomes among patients with advanced non‐small cell lung cancer in the United States.
Published in:
Cancer Medicine, 2023, v. 12, n. 24, p. 21605, doi. 10.1002/cam4.6694
By:
- Yang, Mo;
- MacEwan, Joanna P.;
- Boppudi, Sai Sriteja;
- McClain, Monica R.;
- O'Hara, Richard M.;
- Paik, Paul K.
Publication type:
Article
Amplification of IFN-a-induced STAT1 activation and inflammatory function by Syk and ITAM-containing adaptors.
Published in:
Nature Immunology, 2004, v. 5, n. 11, p. 1181, doi. 10.1038/ni1126
By:
- Tassiulas, Ioannis;
- Hu, Xiaoyu;
- Ho, Hao;
- Kashyap, Yogita;
- Paik, Paul;
- Hu, Yongmei;
- Lowell, Clifford A.;
- Ivashkiv, Lionel B.
Publication type:
Article
Non-small cell lung carcinomas with diffuse coexpression of TTF1 and p40: clinicopathological and genomic features of 14 rare biphenotypic tumours.
Published in:
Histopathology, 2023, v. 82, n. 2, p. 242, doi. 10.1111/his.14801
By:
- Savari, Omid;
- Febres-Aldana, Christopher;
- Chang, Jason C.;
- Fanaroff, Rachel E.;
- Ventura, Katia;
- Bodd, Francis;
- Paik, Paul;
- Vundavalli, Murty;
- Saqi, Anjali;
- Askin, Frederic B.;
- Travis, William D.;
- Rekhtman, Natasha
Publication type:
Article
Non‐small cell lung carcinomas with diffuse coexpression of TTF1 and p40: clinicopathological and genomic features of 14 rare biphenotypic tumours.
Published in:
Histopathology, 2023, v. 82, n. 1, p. 242, doi. 10.1111/his.14801
By:
- Savari, Omid;
- Febres‐Aldana, Christopher;
- Chang, Jason C.;
- Fanaroff, Rachel E.;
- Ventura, Katia;
- Bodd, Francis;
- Paik, Paul;
- Vundavalli, Murty;
- Saqi, Anjali;
- Askin, Frederic B.;
- Travis, William D.;
- Rekhtman, Natasha
Publication type:
Article
Risk of hemoptysis in patients with resected squamous cell and other high-risk lung cancers treated with adjuvant bevacizumab.
Published in:
Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 2, p. 453, doi. 10.1007/s00280-013-2219-5
By:
- Hellmann, Matthew;
- Chaft, Jamie;
- Rusch, Valerie;
- Ginsberg, Michelle;
- Finley, David;
- Kris, Mark;
- Price, Katharine;
- Azzoli, Christopher.;
- Fury, Matthew;
- Riely, Gregory;
- Krug, Lee;
- Downey, Robert;
- Bains, Manjit;
- Sima, Camelia;
- Rizk, Nabil;
- Travis, William;
- Rizvi, Naiyer;
- Paik, Paul
Publication type:
Article
A phase 2 study of weekly albumin-bound paclitaxel (Abraxane®) given as a two-hour infusion.
Published in:
2011
By:
- Paik PK;
- James LP;
- Riely GJ;
- Azzoli CG;
- Miller VA;
- Ng KK;
- Sima CS;
- Heelan RT;
- Kris MG;
- Moore E;
- Rizvi NA;
- Paik, Paul K;
- James, Leonard P;
- Riely, Gregory J;
- Azzoli, Christopher G;
- Miller, Vincent A;
- Ng, Kenneth K;
- Sima, Camelia S;
- Heelan, Robert T;
- Kris, Mark G
Publication type:
journal article
A phase 2 study of weekly albumin-bound paclitaxel (Abraxane) given as a two-hour infusion.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1331, doi. 10.1007/s00280-011-1621-0
By:
- Paik, Paul;
- James, Leonard;
- Riely, Gregory;
- Azzoli, Christopher;
- Miller, Vincent;
- Ng, Kenneth;
- Sima, Camelia;
- Heelan, Robert;
- Kris, Mark;
- Moore, Erin;
- Rizvi, Naiyer
Publication type:
Article
A phase I study of obatoclax mesylate, a Bcl-2 antagonist, plus topotecan in solid tumor malignancies.
Published in:
Cancer Chemotherapy & Pharmacology, 2010, v. 66, n. 6, p. 1079, doi. 10.1007/s00280-010-1265-5
By:
- Paik, Paul K.;
- Rudin, Charles M.;
- Brown, Andrew;
- Rizvi, Naiyer A.;
- Takebe, Naoko;
- Travis, William;
- James, Leonard;
- Ginsberg, Michelle S.;
- Juergens, Rosalyn;
- Markus, Susan;
- Tyson, Leslie;
- Subzwari, Sara;
- Kris, Mark G.;
- Krug, Lee M.
Publication type:
Article
Efficacy and safety of tepotinib in Asian patients with advanced NSCLC with MET exon 14 skipping enrolled in VISION.
Published in:
British Journal of Cancer, 2024, v. 130, n. 10, p. 1679, doi. 10.1038/s41416-024-02615-9
By:
- Kato, Terufumi;
- Yang, James Chih-Hsin;
- Ahn, Myung-Ju;
- Sakai, Hiroshi;
- Morise, Masahiro;
- Chen, Yuh-Min;
- Han, Ji-Youn;
- Yang, Jin-Ji;
- Zhao, Jun;
- Hsia, Te-Chun;
- Berghoff, Karin;
- Bruns, Rolf;
- Vioix, Helene;
- Lang, Simone;
- Johne, Andreas;
- Le, Xiuning;
- Paik, Paul K.
Publication type:
Article
Immune biomarkers and response to checkpoint inhibition of BRAF<sup>V600</sup> and BRAF non-V600 altered lung cancers.
Published in:
2022
By:
- Murciano-Goroff, Yonina R.;
- Pak, Terry;
- Mondaca, Sebastian;
- Flynn, Jessica R.;
- Montecalvo, Joseph;
- Rekhtman, Natasha;
- Halpenny, Darragh;
- Plodkowski, Andrew J.;
- Wu, Stephanie L.;
- Kris, Mark G.;
- Paik, Paul K.;
- Riely, Gregory J.;
- Yu, Helena A.;
- Rudin, Charles M.;
- Hellmann, Matthew D.;
- Land, Josiah D.;
- Buie, Larry W.;
- Heller, Glenn;
- Lito, Piro;
- Yaeger, Rona
Publication type:
journal article
ctDNA Dynamics, Prognostic Markers, and Mechanisms of Resistance in Tepotinib-treated MET exon 14 (METex14) Skipping NSCLC in the VISION Trial.
Published in:
Journal of Oncology Navigation & Survivorship, 2023, v. 14, n. 11, p. 352
By:
- Xiuning Le;
- Garassino, Marina Chiara;
- Myung-Ju Ahn;
- Felip, Enriqueta;
- Cortot, Alexis B.;
- Hiroshi Sakai;
- Mazières, Julien;
- Thomas, Michael;
- Viteri, Santiago;
- Conte, Pierfranco;
- Chih-Hsin Yang, James;
- Iams, Wade Thomas;
- Griesinger, Frank;
- Braggio, Danielle;
- Stroh, Christopher;
- Juraeva, Dilafruz;
- Wang, Danyi;
- Johne, Andreas;
- Paik, Paul K.
Publication type:
Article
Intracranial Activity of Tepotinib in Patients with MET Exon 14 (METex14) Skipping Non-- Small-Cell Lung Cancer (NSCLC) Enrolled in VISION.
Published in:
Journal of Oncology Navigation & Survivorship, 2022, v. 13, n. 11, p. 376
By:
- Hill, Rebecca;
- Leighl, Natasha;
- Bestvina, Christine;
- Patel, Jyoti;
- Xiuning Le;
- Veillon, Remi;
- Anderson, Ian;
- Demedts, Ingel;
- Garassino, Marina Chiara;
- Mazières, Julien;
- Morise, Masahiro;
- Smit, Egbert;
- Eggleton, S. Peter;
- O'Brate, Aurora;
- Bruns, Rolf;
- Adrian, Svenja;
- Paik, Paul K.
Publication type:
Article
Modelling the Effectiveness of Tepotinib in Comparison to Standard-of-Care Treatments in Patients with Advanced Non-small Cell Lung Cancer (NSCLC) Harbouring METex14 Skipping in the UK.
Published in:
Targeted Oncology, 2024, v. 19, n. 2, p. 191, doi. 10.1007/s11523-024-01038-z
By:
- Batteson, Rachael;
- Hook, Emma;
- Wheat, Hollie;
- Hatswell, Anthony J.;
- Vioix, Helene;
- McLean, Thomas;
- Alexopoulos, Stamatia Theodora;
- Baijal, Shobhit;
- Paik, Paul K.
Publication type:
Article
Missing the mark in FGFR1-amplified squamous cell cancer of the lung.
Published in:
2016
By:
- Paik, Paul K.;
- Rudin, Charles M.
Publication type:
Editorial
Association of KRAS and EGFR mutations with survival in patients with advanced lung adenocarcinomas.
Published in:
Cancer (0008543X), 2013, v. 119, n. 2, p. 356, doi. 10.1002/cncr.27730
By:
- Johnson, Melissa L.;
- Sima, Camelia S.;
- Chaft, Jamie;
- Paik, Paul K.;
- Pao, William;
- Kris, Mark G.;
- Ladanyi, Marc;
- Riely, Gregory J.
Publication type:
Article
Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas.
Published in:
Cancer (0008543X), 2012, v. 118, n. 23, p. 5840, doi. 10.1002/cncr.27637
By:
- Paik, Paul K.;
- Johnson, Melissa L.;
- D'Angelo, Sandra P.;
- Sima, Camelia S.;
- Ang, Daphne;
- Dogan, Snjezana;
- Miller, Vincent A.;
- Ladanyi, Marc;
- Kris, Mark G.;
- Riely, Gregory J.
Publication type:
Article
Matching-Adjusted Indirect Comparison (MAIC) of Tepotinib with Other MET Inhibitors for the Treatment of Advanced NSCLC with MET Exon 14 Skipping Mutations.
Published in:
Advances in Therapy, 2022, v. 39, n. 7, p. 3159, doi. 10.1007/s12325-022-02163-9
By:
- Paik, Paul K.;
- Pfeiffer, Boris M.;
- Vioix, Helene;
- Garcia, Andrea;
- Postma, Maarten J.
Publication type:
Article
Long‐term experience with tepotinib in Japanese patients with MET exon 14 skipping NSCLC from the Phase II VISION study.
Published in:
Cancer Science, 2024, v. 115, n. 4, p. 1296, doi. 10.1111/cas.16107
By:
- Morise, Masahiro;
- Kato, Terufumi;
- Matsumoto, Shingo;
- Inoue, Takako;
- Sakamoto, Tomohiro;
- Tokito, Takaaki;
- Atagi, Shinji;
- Kozuki, Toshiyuki;
- Takeoka, Hiroaki;
- Chikamori, Kenichi;
- Shinagawa, Naofumi;
- Tanaka, Hiroshi;
- Horii, Eisuke;
- Adrian, Svenja;
- Bruns, Rolf;
- Johne, Andreas;
- Paik, Paul K.;
- Sakai, Hiroshi
Publication type:
Article
A Prospective Study of Circulating Tumor DNA to Guide Matched Targeted Therapy in Lung Cancers.
Published in:
2019
By:
- Sabari, Joshua K;
- Offin, Michael;
- Stephens, Dennis;
- Ni, Andy;
- Lee, Adrian;
- Pavlakis, Nick;
- Clarke, Stephen;
- Diakos, Connie I;
- Datta, Sutirtha;
- Tandon, Nidhi;
- Martinez, Andres;
- Myers, Mackenzie L;
- Makhnin, Alex;
- Leger, Ysleni;
- Yu, Helena A;
- Paik, Paul K;
- Chaft, Jamie E;
- Kris, Mark G;
- Jeon, Jeong O;
- Borsu, Laetitia A
Publication type:
journal article
Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-20935-9
By:
- Valero, Cristina;
- Lee, Mark;
- Hoen, Douglas;
- Weiss, Kate;
- Kelly, Daniel W.;
- Adusumilli, Prasad S.;
- Paik, Paul K.;
- Plitas, George;
- Ladanyi, Marc;
- Postow, Michael A.;
- Ariyan, Charlotte E.;
- Shoushtari, Alexander N.;
- Balachandran, Vinod P.;
- Hakimi, A. Ari;
- Crago, Aimee M.;
- Long Roche, Kara C.;
- Smith, J. Joshua;
- Ganly, Ian;
- Wong, Richard J.;
- Patel, Snehal G.
Publication type:
Article

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