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- Title
Biocompatibility of transition metal-substituted cobalt ferrite nanoparticles.
- Authors
Sanpo, Noppakun; Tharajak, Jirasak; Li, Yuncang; Berndt, Christopher; Wen, Cuie; Wang, James
- Abstract
Transition metals of copper, zinc, manganese, and nickel were substituted into cobalt ferrite nanoparticles via a sol-gel route using citric acid as a chelating agent. The microstructure and elemental compositions of the nanoparticles were characterized using scanning electron microscopy combined with energy dispersive X-ray spectroscopy. The particle size of the nanoparticles was investigated using particle size analyzer, and the zeta potentials were measured using zeta potential analyzer. The phase components of the synthesized transition metal-substituted cobalt ferrite nanoparticles were studied using Raman spectroscopy. The biocompatibility of the nanoparticles was assessed using osteoblast-like cells. Results indicated that the substitution of transition metals strongly influences the physical, chemical properties, and biocompatibility of the cobalt ferrite nanoparticles.
- Subjects
TRANSITION metals; BIOCOMPATIBILITY; FERRITES; METAL nanoparticles; CHELATING agents; SCANNING electron microscopy; CITRIC acid
- Publication
Journal of Nanoparticle Research, 2014, Vol 16, Issue 7, p1
- ISSN
1388-0764
- Publication type
Article
- DOI
10.1007/s11051-014-2510-3