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- Title
Body Composition Growth Patterns in Early Infancy: A Latent Class Trajectory Analysis of the Ethiopian iABC Birth Cohort.
- Authors
Andersen, Gregers Stig; Wibaek, Rasmus; Kæstel, Pernille; Girma, Tsinuel; Admassu, Bitiya; Abera, Mubarek; Vistisen, Dorte; Jørgensen, Marit Eika; Michaelsen, Kim F.; Friis, Henrik; Wells, Jonathan C.K.; Kaestel, Pernille
- Abstract
<bold>Objective: </bold>The objective of this study was to identify subgroups with distinct fat and fat-free growth patterns in the first 6 months of life and describe predictors of these different patterns.<bold>Methods: </bold>A total of 510 apparently healthy Ethiopian infants were followed from birth to 6 months of age. Each infant had at least three and up to six repeated measurements of fat and fat-free mass using air-displacement plethysmography. Latent class trajectory analyses were used to categorize infants in groups with distinct body composition patterns.<bold>Results: </bold>Four distinct fat mass and two fat-free mass growth patterns were identified. Of the infants measured, 5% presented a delayed fat growth pattern and 3% presented a catch-up fat growth pattern involving low birth weight but a significant fat growth velocity from 2.5 to 6 months. A large class had a high fat level at birth and an accelerated fat growth pattern in early infancy. Fat-free growth was represented by two distinct classes with less variability. Catch-up growth was primarily seen in fat mass.<bold>Conclusions: </bold>We identified distinct patterns of delayed, catch-up, and accelerated fat growth in early infancy. This variability is not detected in regular anthropometric assessment and could be a mechanism linking early growth with later obesity and cardiometabolic risk.
- Subjects
ETHIOPIA; BODY composition; INFANT health; HUMAN body composition; LEAN body mass; BIRTH weight; PUBLIC health
- Publication
Obesity (19307381), 2018, Vol 26, Issue 7, p1225
- ISSN
1930-7381
- Publication type
journal article
- DOI
10.1002/oby.22197