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- Title
Autoimmunity: The nuclear arsenal of autoimmunity.
- Authors
Pisetsky, David S.
- Abstract
The author reflects on the role of DNA in the autoimmune disorders. He said that DNA is the central autoantigen which can form pathogenic immune complexes that stimulate the production of cytokine to drive autoreactivity. He suggests that the challenge is to identify the pathway which is most amenable to therapy
- Subjects
DNA; AUTOIMMUNITY -- Molecular aspects; AUTOIMMUNE diseases; AUTOANTIBODIES
- Publication
Immunology & Cell Biology, 2007, Vol 85, Issue 5, p344
- ISSN
0818-9641
- Publication type
Editorial
- DOI
10.1038/sj.icb.7100074