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- Title
Pneumococcal keratitis: a clinical profile.
- Authors
Parmar, Pragya; Salman, Amjad; Kalavathy, C Munusamy; Jesudasan, CA Nelson; Thomas, Philip A
- Abstract
Abstract Aim: To study the clinical features of pneumococcal keratitis and response to ciprofloxacin therapy. Methods: A retrospective analysis was undertaken of 58 patients with culture-proven pneumococcal keratitis seen over a period of 2 years. Results: Pneumococcal keratitis accounted for 33.3% of bacterial keratitis. Most cases presented with non-severe keratitis (77.5%). Co-existing sac pathology was more frequent in pneumococcal ulcers as compared to non-pneumococcal bacterial ulcers (50%vs 9%, P < 0.001 ). Characteristic clinical features enabling an accurate clinical diagnosis were found in 27.5% and lanceolate diplococci on Gram's stain were identified in 76% of cases. In vitro testing showed a high susceptibility to cephazolin and ciprofloxacin. All patients received ciprofloxacin as first-line therapy. Eighty per cent responded well with complete healing of the ulcer. A second drug was required in 8.5%. Conclusion: Ciprofloxacin therapy can be effective in the treatment of pneumococcal keratitis.
- Subjects
KERATITIS; CIPROFLOXACIN; DACRYOCYSTITIS
- Publication
Clinical & Experimental Ophthalmology, 2003, Vol 31, Issue 1, p44
- ISSN
1442-6404
- Publication type
Article
- DOI
10.1046/j.1442-9071.2003.00598.x