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- Title
Endoscopic mucosal resection vs endoscopic submucosal dissection for rectal carcinoid tumours: a systematic review and meta-analysis.
- Authors
Zhong, D.‐D.; Shao, L.‐M.; Cai, J.‐T.
- Abstract
Aim Endoscopic mucosal resection ( EMR) and endoscopic submucosal dissection ( ESD) are used for the removal of rectal carcinoid tumours. There are no current guidelines or consensus on the optimal treatment strategy for these lesions. A systematic review was conducted to compare the efficacy and safety of ESD and EMR. Method The generation of inclusion criteria and analysis of data were based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses recommendations. A systematic literature review was conducted using the following databases: Medline, Embase, Springer Link, Elsevier Science Direct, Science Citation Index and the Cochrane Library. Only papers comparing treatment of rectal carcinoid tumours by EMR and by ESD were selected. The data collected included the patients' demographic information, interventions made, observed outcome and sources of bias. Results Four papers were included in this systematic review and meta-analysis. ESD was more effective than EMR in complete resection ( OR 0.29; 95% CI 0.14-0.58; P = 0.000). ESD was as safe as EMR [rate difference ( RD) −0.01; 95% CI −0.07 to 0.05; P = 0.675]. Recurrence rates did not differ significantly between the EMR and ESD groups ( RD 0.04; 95% CI −0.01 to 0.09; P = 0.150). The duration of ESD was longer than EMR (standardized mean difference −1.73; 95% CI −2.73 to −0.74; P = 0.001). Conclusion The study indicates that ESD is the better treatment for rectal carcinoid tumours.
- Subjects
SURGICAL excision; HUMAN dissection; RECTAL cancer treatment; CARCINOID; META-analysis
- Publication
Colorectal Disease, 2013, Vol 15, Issue 3, p283
- ISSN
1462-8910
- Publication type
Article
- DOI
10.1111/codi.12069