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- Title
High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle.
- Authors
Kreager, Benjamin C.; Wu, Huaiyu; Chang, Wei-Yi; Moon, Sunho; Mitchell, Josh; Peng, Chang; Huang, Chih-Chung; Muller, Marie; Tian, Jian; Jiang, Xiaoning
- Abstract
To address the need for high-resolution imaging in lung nodule detection and overcome the limitations of the shallow imaging depth associated with high-frequency ultrasound and the complex structure of lung tissue, we successfully integrated 50 MHz ultrasound transducers with 18-gauge biopsy needles. Featuring a miniaturized size of 0.6 × 0.5 × 0.5 mm3, the 50 MHz micromachined 1-3 composite transducer was tested to perform mechanical scanning of a nodule within a lung-tissue-mimicking phantom in vitro. The high-frequency transducer demonstrated the ability to achieve imaging with an axial resolution of 30 μm for measuring nodule edges. Moreover, the integrated biopsy needle prototype exhibited high accuracy (1.74% discrepancy) in estimating nodule area compared to actual dimensions in vitro. These results underscore the promising potential of biopsy-needle-integrated transducers in enhancing the accuracy of endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNA) for clinical applications.
- Subjects
ENDOSCOPIC ultrasonography; NEEDLE biopsy; TRANSDUCERS; VENTILATION; PULMONARY nodules; CLINICAL medicine
- Publication
Biosensors (2079-6374), 2024, Vol 14, Issue 2, p74
- ISSN
2079-6374
- Publication type
Article
- DOI
10.3390/bios14020074