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- Title
Fluorosis and periostitis deformans as complications of prolonged voriconazole treatment.
- Authors
Rad, Babak; Saleem, Mohamed; Grant, Susan; Florkowski, Christopher; Coates, Penelope; Gordon, David; Rankin, Wayne
- Abstract
We describe a case of development of painful periostitis deformans in a 39-year-old woman who was receiving long-term voriconazole treatment for Aspergillus infection as a complication of orthotopic liver transplant. Measurement of fluoride levels strongly supports fluorosis to be the mechanism of the voriconazole-induced periostitis deformans and supports the concept that such measurements might be of use in predicting this complication of long-term voriconazole treatment.
- Subjects
FLUOROSIS; SHIN splints; VORICONAZOLE; LIVER transplantation; TOLIDINE; THERAPEUTICS
- Publication
Annals of Clinical Biochemistry, 2015, Vol 52, Issue 5, p611
- ISSN
0004-5632
- Publication type
Article
- DOI
10.1177/0004563214568873