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Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib.
Published in:
International Journal of Hematology, 2013, v. 98, n. 1, p. 66, doi. 10.1007/s12185-013-1367-z
By:
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kido, Shinsuke;
- Nakano, Ayako;
- Hiasa, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Watanabe, Keiichiro;
- Harada, Takeshi;
- Fujii, Shiro;
- Takeuchi, Kyoko;
- Kagawa, Kumiko;
- Ozaki, Shuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Association of Th1 and Th2 cytokines with transient inflammatory reaction during lenalidomide plus dexamethasone therapy in multiple myeloma.
Published in:
International Journal of Hematology, 2013, v. 97, n. 6, p. 743, doi. 10.1007/s12185-013-1321-0
By:
- Harada, Takeshi;
- Ozaki, Shuji;
- Oda, Asuka;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Targeting myeloma-osteoclast interaction with Vγ9Vδ2 T cells.
Published in:
2011
By:
- Cui, Qu;
- Shibata, Hironobu;
- Oda, Asuka;
- Amou, Hiroe;
- Nakano, Ayako;
- Yata, Kenichiro;
- Hiasa, Masahiro;
- Watanabe, Keiichiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Harada, Takeshi;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Ozaki, Shuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
journal article
Delayed treatment with vitamin C and N-acetyl-L-cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib.
Published in:
2011
By:
- Nakano, Ayako;
- Abe, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Hiasa, Masahiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Harada, Takeshi;
- Fujii, Shirou;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Watanabe, Takashi;
- Ozaki, Shuji;
- Matsumoto, Toshio
Publication type:
journal article
Transient inflammatory reaction during lenalidomide plus reduced-dose dexamethasone therapy in two patients with relapsed multiple myeloma.
Published in:
2011
By:
- Ozaki, Shuji;
- Harada, Takeshi;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Nakano, Ayako;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Abe, Masahiro;
- Matsumoto, Toshio
Publication type:
Case Study
Marked improvement of platelet transfusion refractoriness after bortezomib therapy in multiple myeloma.
Published in:
2009
By:
- Miki, Hirokazu;
- Ozaki, Shuji;
- Tanaka, Osamu;
- Lee, Etsuko;
- Takimoto, Tomomi;
- Watanabe, Hirofumi;
- Fujii, Shiro;
- Nakamura, Shingen;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Yata, Ken-ichiro;
- Abe, Masahiro;
- Kagami, Shoji;
- Matsumoto, Toshio
Publication type:
journal article
Therapy with bortezomib plus dexamethasone induces osteoblast activation in responsive patients with multiple myeloma.
Published in:
2007
By:
- Ozaki, Shuji;
- Tanaka, Osamu;
- Fujii, Shiro;
- Shigekiyo, Yuri;
- Miki, Hirokazu;
- Choraku, Masahito;
- Kagawa, Kumiko;
- Asano, Jin;
- Takeuchi, Kyoko;
- Kitazoe, Ken-ichi;
- Hashimoto, Toshihiro;
- Abe, Masahiro;
- Matsumoto, Toshio
Publication type:
journal article
Correlation between high serum alkaline phosphatase levels and denosumab‐related hypocalcemia in patients with multiple myeloma.
Published in:
British Journal of Haematology, 2019, v. 186, n. 2, p. 355, doi. 10.1111/bjh.15837
By:
- Miki, Hirokazu;
- Nakamura, Shingen;
- Oura, Masahiro;
- Hamano, Hirofumi;
- Ikuta, Kenji;
- Okada, Naoto;
- Okamoto, Yasunobu;
- Sogabe, Kimiko;
- Takahashi, Mamiko;
- Iwasa, Masami;
- Udaka, Kengo;
- Harada, Takeshi;
- Kurahashi, Kiyoe;
- Fujii, Shiro;
- Yoshida, Sumiko;
- Kagawa, Kumiko;
- Endo, Itsuro;
- Aihara, Ken‐ichi;
- Abe, Masahiro
Publication type:
Article
Class 1 HDAC and HDAC6 inhibition inversely regulates CD38 induction in myeloma cells via interferon‐α and ATRA.
Published in:
British Journal of Haematology, 2019, v. 185, n. 5, p. 969, doi. 10.1111/bjh.15673
By:
- Bat‐Erdene, Ariunzaya;
- Nakamura, Shingen;
- Oda, Asuka;
- Iwasa, Masami;
- Teramachi, Jumpei;
- Ashtar, Mohannad;
- Harada, Takeshi;
- Miki, Hirokazu;
- Tenshin, Hirofumi;
- Hiasa, Masahiro;
- Fujii, Shiro;
- Sogabe, Kimiko;
- Oura, Masahiro;
- Udaka, Kengo;
- Kagawa, Kumiko;
- Yoshida, Sumiko;
- Aihara, Ken‐ichi;
- Kurahashi, Kiyoe;
- Endo, Itsuro;
- Abe, Masahiro
Publication type:
Article
Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma.
Published in:
British Journal of Haematology, 2018, v. 180, n. 4, p. 581, doi. 10.1111/bjh.14388
By:
- Teramachi, Jumpei;
- Hiasa, Masahiro;
- Oda, Asuka;
- Harada, Takeshi;
- Nakamura, Shingen;
- Amachi, Ryota;
- Tenshin, Hirofumi;
- Iwasa, Masami;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Miki, Hirokazu;
- Kurahashi, Kiyoe;
- Yoshida, Sumiko;
- Endo, Itsuro;
- Haneji, Tatsuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Unique anti‐myeloma activity by thiazolidine‐2,4‐dione compounds with Pim inhibiting activity.
Published in:
British Journal of Haematology, 2018, v. 180, n. 2, p. 246, doi. 10.1111/bjh.15033
By:
- Fujii, Shiro;
- Nakamura, Shingen;
- Oda, Asuka;
- Miki, Hirokazu;
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Hiasa, Masahiro;
- Bat‐Erdene, Ariunzaya;
- Maeda, Yusaku;
- Oura, Masahiro;
- Takahashi, Mamiko;
- Iwasa, Masami;
- Endo, Itsuro;
- Yoshida, Sumiko;
- Aihara, Ken‐ichi;
- Kurahashi, Kiyoe;
- Harada, Takeshi;
- Kagawa, Kumiko;
- Nakao, Michiyasu;
- Sano, Shigeki
Publication type:
Article
Frequent bleeding symptoms associated with autoimmune acquired factor XIII/13 deficiency due to anti‐factor XIII A and B subunit antibodies.
Published in:
American Journal of Hematology, 2022, v. 97, n. 11, p. 1497, doi. 10.1002/ajh.26685
By:
- Ozaki, Shuji;
- Mizuguchi, Makiko;
- Okamoto, Yasunobu;
- Yagi, Hikaru;
- Kagawa, Kumiko;
- Shibata, Hironobu;
- Yoda, Keiji;
- Souri, Masayoshi;
- Ichinose, Akitada
Publication type:
Article
Combination with a Defucosylated Anti-HM1.24 Monoclonal Antibody plus Lenalidomide Induces Marked ADCC against Myeloma Cells and Their Progenitors.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083905
By:
- Harada, Takeshi;
- Ozaki, Shuji;
- Oda, Asuka;
- Tsuji, Daisuke;
- Ikegame, Akishige;
- Iwasa, Masami;
- Udaka, Kengo;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kagawa, Kumiko;
- Kuroda, Yoshiaki;
- Kawai, Shigeto;
- Itoh, Kohji;
- Yamada-Okabe, Hisafumi;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Inhibition of TACE Activity Enhances the Susceptibility of Myeloma Cells to TRAIL.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031594
By:
- Kagawa, Kumiko;
- Nakano, Ayako;
- Miki, Hirokazu;
- Oda, Asuka;
- Amou, Hiroe;
- Takeuchi, Kyoko;
- Nakamura, Shingen;
- Harada, Takeshi;
- Fujii, Shiro;
- Yata, Kenichiro;
- Ozaki, Shuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Glycolysis Inhibition Inactivates ABC Transporters to Restore Drug Sensitivity in Malignant Cells.
Published in:
PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027222
By:
- Nakano, Ayako;
- Tsuji, Daisuke;
- Miki, Hirokazu;
- Qu Cui;
- Sayed, Salah Mohamed El;
- Ikegame, Akishige;
- Oda, Asuka;
- Amou, Hiroe;
- Nakamura, Shingen;
- Harada, Takeshi;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Sakai, Akira;
- Ozaki, Shuji;
- Okano, Kazuma;
- Nakamura, Takahiro;
- Itoh, Kohji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
TGF-β Inhibition Restores Terminal Osteoblast Differentiation to Suppress Myeloma Growth.
Published in:
PLoS ONE, 2010, v. 5, n. 3, p. 1, doi. 10.1371/journal.pone.0009870
By:
- Takeuchi, Kyoko;
- Abe, Masahiro;
- Hiasa, Masahiro;
- Oda, Asuka;
- Amou, Hiroe;
- Kido, Shinsuke;
- Harada, Takeshi;
- Tanaka, Osamu;
- Miki, Hirokazu;
- Nakamura, Shingen;
- Nakano, Ayako;
- Kagawa, Kumiko;
- Yata, Kenichiro;
- Ozaki, Shuji;
- Matsumoto, Toshio
Publication type:
Article
The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat.
Published in:
Cancers, 2020, v. 12, n. 4, p. 929, doi. 10.3390/cancers12040929
By:
- Ashtar, Mohannad;
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Bat-Erdene, Ariunzaya;
- Hiasa, Masahiro;
- Oda, Asuka;
- Tanimoto, Kotaro;
- Shimizu, So;
- Higa, Yoshiki;
- Harada, Takeshi;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Nakamura, Shingen;
- Fujii, Shiro;
- Sumitani, Ryohei;
- Miki, Hirokazu;
- Udaka, Kengo;
- Takahashi, Mamiko;
- Kagawa, Kumiko;
- Endo, Itsuro
Publication type:
Article
Polyclonal Immunoglobulin Recovery after Autologous Stem Cell Transplantation Is an Independent Prognostic Factor for Survival Outcome in Patients with Multiple Myeloma.
Published in:
Cancers, 2020, v. 12, n. 1, p. 12, doi. 10.3390/cancers12010012
By:
- Ozaki, Shuji;
- Harada, Takeshi;
- Yagi, Hikaru;
- Sekimoto, Etsuko;
- Shibata, Hironobu;
- Shigekiyo, Toshio;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kagawa, Kumiko;
- Abe, Masahiro
Publication type:
Article
Intravenous busulfan-based conditioning with autologous stem cell transplantation for refractory B-cell lymphoma with central nervous system involvement.
Published in:
Journal of Medical Investigation, 2021, v. 68, n. 1/2, p. 196, doi. 10.2152/jmi.68.196
By:
- Mamiko Takahashi;
- Ryohei Sumitani;
- Taiki Hori;
- Jumpei Murai;
- Shiyori Kawata;
- Masahiro Oura;
- Kimiko Sogabe;
- Takeshi Harada;
- Shiro Fujii;
- Hirokazu Miki;
- Kumiko Kagawa;
- Masahiro Abe;
- Shingen Nakamura
Publication type:
Article
Comparison of Autologous Hematopoietic Cell Transplantation and Chemotherapy as Postremission Treatment in Non-M3 Acute Myeloid Leukemia in First Complete Remission.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2012, v. 12, n. 6, p. 444, doi. 10.1016/j.clml.2012.07.004
By:
- Kensuke Usuki;
- Saiko Kurosawa;
- Naoyuki Uchida;
- Kazuaki Yakushiji;
- Fusako Waki;
- Eijo Matsuishi;
- Kumiko Kagawa;
- Tatsuo Furukawa;
- Yoshinobu Maeda;
- Manabu Shimoyama;
- Hiroatsu Ago;
- Yujiro Yamano;
- Shingo Yano;
- Naohito Fujishima;
- Yasushi Takamatsu;
- Tetsuya Eto;
- Michihiro Hidaka;
- Hitoshi Matsuoka;
- Takahiro Fukuda
Publication type:
Article
Incidence and predictors of recurrent sick leave in survivors who returned to work after allogeneic hematopoietic cell transplantation.
Published in:
Journal of Cancer Survivorship, 2023, v. 17, n. 3, p. 781, doi. 10.1007/s11764-022-01250-8
By:
- Kurosawa, Saiko;
- Yamaguchi, Takuhiro;
- Mori, Ayako;
- Matsuura, Tomoko;
- Masuko, Masayoshi;
- Murata, Makoto;
- Tashiro, Haruko;
- Kako, Shinichi;
- Satake, Atsushi;
- Hagihara, Maki;
- Ota, Shuichi;
- Saito, Takeshi;
- Kagawa, Kumiko;
- Matsuo, Yayoi;
- Itonaga, Hidehiro;
- Uoshima, Nobuhiko;
- Yamaguchi, Hiroki;
- Naito, Kensuke;
- Takahashi, Miyako;
- Fukuda, Takahiro
Publication type:
Article
Polyclonal immunoglobulin recovery after autologous stem cell transplantation is an independent prognosis factor for survival in patients with multiple myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e215, doi. 10.1016/j.clml.2019.09.358
By:
- Ozaki, Shuji;
- Harada, Takeshi;
- Yagi, Hikaru;
- Sekimoto, Etsuko;
- Shibata, Hironobu;
- Shigekiyo, Toshio;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kagawa, Kumiko;
- Abe, Masahiro
Publication type:
Article
Synergistic targeting of Sp1 in myeloma cells with hyperthermia plus proteasome inhibitors.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e132, doi. 10.1016/j.clml.2019.09.219
By:
- Miki, Hirokazu;
- Nakamura, Shingen;
- Bat-Erdene, Ariunzaya;
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Oda, Asuka;
- Kawata, Shiyori;
- Hori, Taiki;
- Murai, Jumpei;
- Sumitani, Ryohei;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Takahashi, Mamiko;
- Udaka, Kengo;
- Harada, Takeshi;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Abe, Masahiro
Publication type:
Article
Targeting myeloma metabolisms regulated by HDAC1-IRF4 axis can be a novel therapeutic strategy.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e105, doi. 10.1016/j.clml.2019.09.173
By:
- Harada, Takeshi;
- Oda, Asuka;
- Tenshin, Hirofumi;
- Teramachi, Jumpei;
- Oura, Masahiro;
- Sogabe, Kimiko;
- Fujii, Shiro;
- Nakamura, Shingen;
- Miki, Hirokazu;
- Kagawa, Kumiko;
- Ozaki, Shuji;
- Hideshima, Teru;
- Anderson, Kenneth C.;
- Abe, Masahiro
Publication type:
Article
Acute accumulation of PIM2 and NRF2 and recovery of β5 subunit activity mitigate multiple myeloma cell susceptibility to proteasome inhibitors.
Published in:
International Journal of Hematology, 2024, v. 119, n. 3, p. 303, doi. 10.1007/s12185-023-03705-9
By:
- Sogabe, Kimiko;
- Nakamura, Shingen;
- Higa, Yoshiki;
- Miki, Hirokazu;
- Oda, Asuka;
- Maruhashi, Tomoko;
- Sumitani, Ryohei;
- Oura, Masahiro;
- Takahashi, Mamiko;
- Nakamura, Masafumi;
- Maeda, Yusaku;
- Hara, Tomoyo;
- Yamagami, Hiroki;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Ozaki, Shuji;
- Kurahashi, Kiyoe;
- Endo, Itsuro;
- Aihara, Ken-ichi;
- Nakaue, Emiko
Publication type:
Article
Clinical relevance of high-risk cytogenetic abnormalities and the second revision of the International Staging System (R2-ISS) in patients with multiple myeloma in clinical practice.
Published in:
International Journal of Hematology, 2023, v. 117, n. 5, p. 718, doi. 10.1007/s12185-023-03541-x
By:
- Mizuguchi, Makiko;
- Okamoto, Yasunobu;
- Yagi, Hikaru;
- Kagawa, Kumiko;
- Sekimoto, Etsuko;
- Shibata, Hironobu;
- Shigekiyo, Toshio;
- Ozaki, Shuji
Publication type:
Article
KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts.
Published in:
British Journal of Haematology, 2011, v. 155, n. 3, p. 328, doi. 10.1111/j.1365-2141.2011.08844.x
By:
- Miki, Hirokazu;
- Ozaki, Shuji;
- Nakamura, Shingen;
- Oda, Asuka;
- Amou, Hiroe;
- Ikegame, Akishige;
- Watanabe, Keiichiro;
- Hiasa, Masahiro;
- Cui, Qu;
- Harada, Takeshi;
- Fujii, Shiro;
- Nakano, Ayako;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Yata, Ken-ichiro;
- Sakai, Akira;
- Abe, Masahiro;
- Matsumoto, Toshio
Publication type:
Article
Cryptosporidiosis in a transplant recipient with severe intractable diarrhea: Detection of <italic>Cryptosporidium</italic> oocysts by intestinal biopsies.
Published in:
Transplant Infectious Disease, 2018, v. 20, n. 2, p. 1, doi. 10.1111/tid.12826
By:
- Kagawa, Kumiko;
- Fujino, Hikaru;
- Sogabe, Kimiko;
- Takahashi, Mamiko;
- Maruhashi, Tomoko;
- Udaka, Kengo;
- Iwasa, Masami;
- Fujii, Shiro;
- Nakamura, Shingen;
- Abe, Masahiro;
- Miki, Hirokazu
Publication type:
Article
Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate.
Published in:
Journal of Bioenergetics & Biomembranes, 2012, v. 44, n. 1, p. 31, doi. 10.1007/s10863-012-9412-9
By:
- Nakano, Ayako;
- Miki, Hirokazu;
- Nakamura, Shingen;
- Harada, Takeshi;
- Oda, Asuka;
- Amou, Hiroe;
- Fujii, Shiro;
- Kagawa, Kumiko;
- Takeuchi, Kyoko;
- Ozaki, Shuji;
- Matsumoto, Toshio;
- Abe, Masahiro
Publication type:
Article
Constitutional pericentric inversion of chromosome 16, inv(16)(p13.1q22), mimicking acute myeloid leukemia.
Published in:
2022
By:
- Ozaki, Shuji;
- Umeda, Honami;
- Mizuguchi, Makiko;
- Okamoto, Yasunobu;
- Yagi, Hikaru;
- Kagawa, Kumiko;
- Shibata, Hironobu
Publication type:
Case Study

Found: 30