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- Title
Pain at the Injection Site of Subcutaneously Administered Erythropoietin in Maintenance Hemodialysis Patients: A Comparison of Two Brands of Erythropoietin.
- Authors
Veys, Nic; Vanholder, Raymond; Lameire, Norbert
- Abstract
Local pain due to subcutaneous erythropoietin (EPO) injection into the thigh was studied using a verbal score ranging from 0 to 4. Equivoluminous doses of epoetin-α (Cilag) and epoetin-β (Boehringer) were compared in 2 controlled single-blind experiments: 10 dialysis patients were treated at random for 4 weeks at consecutive sessions with both brands of EPO, and 40 patients were treated in 1 session only with the 2 brands simultaneously. Pain scores were 1.12 ± 0.28 versus 0.15 ± 0.06 (p < 0.05) and 1.75 ± 0.19 versus 0.08 ± 0.04 for epoetin-α and epoetin-β, respectively (p < 0.001). Treatment acceptance was 48% for epoetin-α versus 83% for epoetin-β (p < 0.05). Copyright © 1992 S. Karger AG, Basel
- Publication
American Journal of Nephrology, 1992, Vol 12, Issue 1/2, p68
- ISSN
0250-8095
- Publication type
Article
- DOI
10.1159/000168420