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- Title
Efectos de la suplementación de carnitina sobre el nivel de fatiga muscular del gastrocnemio de ratas entrenadas y sedentarias.
- Authors
Gomez Campos, Rossana; de Arruda, Miguel; Pinhero Ramos, Fabio; Cossio-Bolaños, Marco Antonio
- Abstract
L-carnitine, considered to be of great value in metabolic processes, plays an important role in the mitochondrial β-oxidation process. It may be used to improve athletic performance and to maintain a higher workload during exercise. This study aimed to investigate the effect of L-carnitine supplementation on muscle fatigue in sciatic nerve-gastrocnemius muscle preparations in sedentary and trained rats. The animals were divided into 4 groups: non-supplemented sedentary (NSS), supplemented sedentary (SS), non-supplemented trained (NST), and supplemented trained (ST) rats. The animals were trained in daily 1-h sessions (5 days/week) and received chronic oral L-carnitine supplementation (1 mg/mL) for 4 weeks. Muscle fatigue was determined by supramaximal tetanic stimulation of the sciatic nerve (50 Hz). Time values for strength reduction were significantly different (p<0.05) between NSS vs. SS and NST vs. ST rats. No significant differences were observed between SS vs. ST and NST vs. NSS rats. These findings demonstrate that L-carnitine lengthen the time required for induction of muscle fatigue.
- Subjects
ANALYSIS of variance; ANIMAL experimentation; CARNITINE; DIETARY supplements; RATS; STATISTICS; DATA analysis; CALF muscles; INTER-observer reliability; DESCRIPTIVE statistics; MUSCLE fatigue
- Publication
Brazilian Journal of Kineanthropometry & Human Performance, 2012, Vol 14, Issue 3, p324
- ISSN
1415-8426
- Publication type
Article
- DOI
10.5007/1980-0037.2012v14n3p324