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- Title
Microwave-assisted one-pot syntheses of 4-aminoquinazolines.
- Authors
Song, Wenting; He, Shunli; Yuan, Zeli; Yu, Guangqing; Wu, Di; Wu, Qing; Zhang, Minqing; Chen, Yongzheng; Hu, Qinghong
- Abstract
A simple, environmentally friendly, one-pot method for the synthesis of 4-aminoquinazolines using microwave irradiation has been developed. Structures of derivatives 3, 4, and 5 were confirmed by single-crystal X-ray diffraction. The in vitro cytotoxicity of each compound was investigated using an MTT assay with A549 and HepG2 cell lines to calculate half-maximal inhibitory concentrations.
- Publication
Green Processing & Synthesis, 2016, Vol 5, Issue 3, p247
- ISSN
2191-9542
- Publication type
Article
- DOI
10.1515/gps-2015-0121