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Opportunities for Community Pharmacists to Counsel Patients With Epilepsy and Seizure Clusters to Overcome Barriers and Foster Appropriate Treatment.
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- Journal of Pharmacy Practice, 2024, v. 37, n. 1, p. 190, doi. 10.1177/08971900221126570
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Evaluation of Pharmacokinetics and Dose Proportionality of Diazepam After Intranasal Administration of NRL‐1 to Healthy Volunteers.
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- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 6, p. 719, doi. 10.1002/cpdd.767
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- Article
Improvement of Intranasal Drug Delivery with Intravail<sup>®</sup> Alkylsaccharide Excipient as a Mucosal Absorption Enhancer Aiding in the Treatment of Conditions of the Central Nervous System.
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- Drugs in R&D, 2021, v. 21, n. 4, p. 361, doi. 10.1007/s40268-021-00360-5
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Optimizing Absorption for Intranasal Delivery of Drugs Targeting the Central Nervous System Using Alkylsaccharide Permeation Enhancers.
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- Pharmaceutics, 2023, v. 15, n. 8, p. 2119, doi. 10.3390/pharmaceutics15082119
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- Article
Safety of Diazepam Nasal Spray in Pediatric Patients With Developmental Epileptic Encephalopathies: Results From a Long-term Phase 3 Safety Study.
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- Journal of Child Neurology, 2023, v. 38, n. 6/7, p. 389, doi. 10.1177/08830738231185424
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- Article
Dosing feasibility and tolerability of intranasal diazepam in adults with epilepsy.
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- Epilepsia (Series 4), 2014, v. 55, n. 10, p. 1544, doi. 10.1111/epi.12755
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- Article
Diazepam nasal spray administration is effective to control seizure clusters irrespective of time of day.
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- Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2024.1335421
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Taking a Newer, Faster, Intranasal Route: A Narrative Review of Transitioning to a Less-Invasive Rescue Treatment for Seizure Clusters.
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- Patient Preference & Adherence, 2024, v. 18, p. 383, doi. 10.2147/PPA.S447028
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Implications of Seizure-Cluster Treatment on Healthcare Utilization: Use of Approved Rescue Medications.
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- Neuropsychiatric Disease & Treatment, 2022, v. 18, p. 2431, doi. 10.2147/NDT.S376104
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Short-Term Impact of Seizures and Mitigation Opportunities.
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- Current Neurology & Neuroscience Reports, 2024, v. 24, n. 8, p. 303, doi. 10.1007/s11910-024-01350-1
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- Article
Alternative Approaches for Addressing Acute Agitation in Schizophrenia and Bipolar Disorder.
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- Primary Care Companion for CNS Disorders (2155-7772), 2024, v. 26, n. 1, p. e1, doi. 10.4088/PCC.23nr03596
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- Article
Benzodiazepines for the Treatment of Seizure Clusters.
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- CNS Drugs, 2024, v. 38, n. 2, p. 125, doi. 10.1007/s40263-023-01060-1
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- Article
Advanced Lipid Technologies® (ALT®): A Proven Formulation Platform to Enhance the Bioavailability of Lipophilic Compounds.
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- Journal of Drug Delivery, 2019, p. 1, doi. 10.1155/2019/1957360
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- Article
Development of a novel dosing paradigm to model diazepam rescue therapy in preclinical seizure and epilepsy models.
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- Epilepsia Open, 2024, v. 9, n. 4, p. 1575, doi. 10.1002/epi4.12954
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- Article
Safety and effectiveness of diazepam nasal spray in male and female patients: Post hoc analysis of data from a phase 3 safety study.
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- Epilepsia Open, 2024, v. 9, n. 2, p. 793, doi. 10.1002/epi4.12907
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- Article
Intracerebral electrographic activity following a single dose of diazepam nasal spray: A pilot study.
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- Epilepsia Open, 2024, v. 9, n. 1, p. 380, doi. 10.1002/epi4.12890
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- Article
Consistent safety and tolerability of Valtoco<sup>®</sup> (diazepam nasal spray) in relationship to usage frequency in patients with seizure clusters: Interim results from a phase 3, long‐term, open‐label, repeat‐dose safety study.
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- Epilepsia Open, 2021, v. 6, n. 3, p. 504, doi. 10.1002/epi4.12494
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- Article
Safety profile of dalfampridine extended release in multiple sclerosis: 5-year postmarketing experience in the United States.
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- Drug, Healthcare & Patient Safety, 2015, v. 7, p. 169, doi. 10.2147/DHPS.S97113
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- Article
Predictive value of P300 event-related potentials compared with EEG and somatosensory evoked potentials in non-traumatic coma.
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- Acta Neurologica Scandinavica, 1993, v. 87, n. 5, p. 423, doi. 10.1111/j.1600-0404.1993.tb04128.x
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Analysis of seizure‐cluster circadian periodicity from a long‐term, open‐label safety study of diazepam nasal spray.
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- Epilepsia (Series 4), 2024, v. 65, n. 4, p. 920, doi. 10.1111/epi.17911
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A comparison of statistical versus clinical classifiers of seizure clustering in women with catamenial and noncatamenial epilepsy.
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- Epilepsia (Series 4), 2023, v. 64, n. 6, p. 1507, doi. 10.1111/epi.17588
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- Article
Significant improvements in SEIzure interVAL (time between seizure clusters) across time in patients treated with diazepam nasal spray as intermittent rescue therapy for seizure clusters.
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- Epilepsia (Series 4), 2022, v. 63, n. 10, p. 2684, doi. 10.1111/epi.17385
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Future opportunities for research in rescue treatments.
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- Epilepsia (Series 4), 2022, v. 63, p. S55, doi. 10.1111/epi.17363
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Lack of clinically relevant differences in safety and pharmacokinetics after second‐dose administration of intranasal diazepam within 4 h for acute treatment of seizure clusters: A population analysis.
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- Epilepsia (Series 4), 2022, v. 63, n. 7, p. 1714, doi. 10.1111/epi.17249
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- Article
Use of second doses of Valtoco® (diazepam nasal spray) across 24 hours after the initial dose for out‐of‐hospital seizure clusters: Results from a phase 3, open‐label, repeat‐dose safety study.
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- Epilepsia (Series 4), 2022, v. 63, n. 4, p. 836, doi. 10.1111/epi.17177
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- Article
Final results from a Phase 3, long‐term, open‐label, repeat‐dose safety study of diazepam nasal spray for seizure clusters in patients with epilepsy.
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- Epilepsia (Series 4), 2021, v. 62, n. 10, p. 2485, doi. 10.1111/epi.17041
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- Article
Evaluation of diazepam nasal spray in patients with epilepsy concomitantly using maintenance benzodiazepines: An interim subgroup analysis from a phase 3, long‐term, open‐label safety study.
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- Epilepsia (Series 4), 2021, v. 62, n. 6, p. 1442, doi. 10.1111/epi.16901
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Overcoming the challenges of developing an intranasal diazepam rescue therapy for the treatment of seizure clusters.
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- Epilepsia (Series 4), 2021, v. 62, n. 4, p. 846, doi. 10.1111/epi.16847
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Pharmacokinetics and safety of VALTOCO (NRL‐1; diazepam nasal spray) in patients with epilepsy during seizure (ictal/peri‐ictal) and nonseizure (interictal) conditions: A phase 1, open‐label study.
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- Epilepsia (Series 4), 2020, v. 61, n. 5, p. 935, doi. 10.1111/epi.16506
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- Article
Practical Questions About Rescue Medications for Acute Treatment of Seizure Clusters in Children and Adolescents with Epilepsy in the USA: Expanding Treatment Options to Address Unmet Needs.
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- Pediatric Drugs, 2024, v. 26, n. 1, p. 49, doi. 10.1007/s40272-023-00601-x
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- Article
Assessment of Colour Vision in Epileptic Patients Exposed to Single-Drug Therapy.
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- European Neurology, 1999, v. 41, n. 4, p. 201, doi. 10.1159/000008051
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- Article
Dalfampridine Effects Beyond Walking Speed in Multiple Sclerosis.
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- International Journal of MS Care, 2015, v. 17, n. 6, p. 275, doi. 10.7224/1537-2073.2014-036
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- Article
Rapid Rescue Treatment with Diazepam Nasal Spray Leads to Faster Seizure Cluster Termination in Epilepsy: An Exploratory Post Hoc Cohort Analysis.
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- Neurology & Therapy, 2024, v. 13, n. 1, p. 221, doi. 10.1007/s40120-023-00568-4
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- Article
Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies.
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- Neurology & Therapy, 2023, v. 12, n. 5, p. 1439, doi. 10.1007/s40120-023-00515-3
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- Article
Risk of Antipsychotic Drug Use in Patients with Alzheimer's Disease Treated with Rivastigmine.
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- Drugs & Aging, 2004, v. 21, n. 6, p. 395, doi. 10.2165/00002512-200421060-00004
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- Article
DALFAMPRIDINE IN CHRONIC SENSORIMOTOR DEFICITS AFTER ISCHEMIC STROKE: A PROOF OF CONCEPT STUDY.
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- Journal of Rehabilitation Medicine (Stiftelsen Rehabiliteringsinformation), 2015, v. 47, n. 10, p. 924, doi. 10.2340/16501977-2033
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Pharmacokinetic-pharmacodynamic crossover comparison of two levodopa extension strategies.
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- Movement Disorders, 2009, v. 24, n. 9, p. 1319, doi. 10.1002/mds.22587
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- Article
An open-label evaluation of the tolerability and safety of Stalevo® (carbidopa, levodopa and entacapone) in Parkinson’s disease patients experiencing wearing-off.
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- Journal of Neural Transmission, 2005, v. 112, n. 2, p. 221, doi. 10.1007/s00702-004-0184-1
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- Article