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- Title
The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases.
- Authors
Bridger, Joanna M.; Brindley, Paul J.; Knight, Matty
- Abstract
The article focuses on aspects of the snail or schistosome relationship elucidating common pathways to enable both snails and humans to accommodate parasitism by schistosomes in view of physiological and immunological environments. It notes that the excretory or secretory products (ESPs) of the miracidium include the stress-inducing factor. Gene repositioning in B. glabrata by schistosomes exemplifies how a eukaryotic pathogen influences hijack of the genome behavior of its host.
- Subjects
SCHISTOSOMA; SNAILS; EUKARYOTIC cells; PATHOGENIC microorganisms; GENOMES
- Publication
PLoS Neglected Tropical Diseases, 2018, Vol 12, Issue 8, p1
- ISSN
1935-2727
- Publication type
Article
- DOI
10.1371/journal.pntd.0006552