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- Title
Sepsis of unknown origin with multiorgan failure syndrome: Think of hemophagocytic lymphohistiocytosis.
- Authors
Maheshwari, Namrata; Mandal, Amit Kumar; Sahni, Neeru
- Abstract
Hemophagocytic lymphohistiocytosis is a clinic pathologic entity characterized by increased proliferation and activation of benign macrophages with hemophagocytosis throughout the reticuloendothelial system. It is a potentially lethal disorder due to an uncontrolled immune response to a triggering agent. HPS may be primary, or secondary to malignancy, infections, auto-immune diseases, and pharmacotherapy. HPS is a rare, but life-threatening complication. Herein, we described a female patient with HPS with secondary sepsis. Our objective was to raise the importance of early diagnosis of HFS by presenting a representative case.
- Subjects
MULTIPLE organ failure; SEPSIS; DIFFERENTIAL diagnosis; INTENSIVE care units; PHAGOCYTES; HEMOPHAGOCYTIC lymphohistiocytosis; DIAGNOSIS
- Publication
Indian Journal of Critical Care Medicine, 2015, Vol 19, Issue 7, p419
- ISSN
0972-5229
- Publication type
Article
- DOI
10.4103/0972-5229.160291