We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Olfactory function and olfactory bulb volume in Wilson's disease.
- Authors
Degirmenci, Nazan; Veyseller, Bayram; Hanagasi, Hasmet; Bilgic, Basar; Gurbuz, Defne; Toprak, Ali; Ozturan, Orhan
- Abstract
Purpose: To evaluate the olfactory function and the olfactory bulb (OB) volume changes in Wilson's Disease (WD) patients.Methods: A prospective, controlled, single-blinded study was planned. 12 patients with WD (Group 1) and 12 healthy subjects (Group 2) were included in the study. Connecticut Chemosensory Clinical Research Center (CCCRC) test was applied to evaluate olfactory functions. OB volumes were measured with a 1.5 T General Electric Signa Excite MRI scanner.Results: There was a significant difference between the CCCRC scores of the two groups (p < 0.05). The difference of the OB volumes of the two groups was insignificant (p > 0.05).Conclusions: WD patients are likely to experience olfactory dysfunction, so its assessment may be a useful tool to the follow-up care of these patients, although further studies are needed to evaluate correlations in WD evolution.
- Subjects
HEPATOLENTICULAR degeneration; OLFACTORY bulb; EVOLUTIONARY theories
- Publication
European Archives of Oto-Rhino-Laryngology, 2019, Vol 276, Issue 1, p139
- ISSN
0937-4477
- Publication type
Article
- DOI
10.1007/s00405-018-5216-9