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- Title
Correction: Saratale et al. Significance of Immune Status of SARS-CoV-2 Infected Patients in Determining the Efficacy of Therapeutic Interventions. J. Pers. Med. 2022, 12 , 349.
- Authors
Saratale, Ganesh Dattatraya; Shin, Han-Seung; Shinde, Surendra Krushna; Kim, Dae-Young; Saratale, Rijuta Ganesh; Kadam, Avinash Ashok; Kumar, Manu; Bahkali, Ali Hassan; Syed, Asad; Ghodake, Gajanan Sampatrao
- Abstract
Emerging therapeutic approaches against COVID-19 disease: (1) antibody-based therapeutics against the S protein (either via adoptive transfer of vaccination) to avoid progression of severe infections; (2) application of protease inhibitors against serine protease (TMPRSS2) prevents cleavage of S protein; (3) SRS-CoV-2 virus-specific memory CD8+ T cells from vaccination or earlier infection; (4) a new treatment approach targets the symptoms of cytokine storm, wherein the blood of infected patients is passed through customized filtration columns to capture pro-inflammatory cytokines before the pureblood returns to patients. Intensive care or appropriate treatment is recommended for hospitalized severe SARS-CoV-2 patients who exhibit elevated levels of biomarkers in blood plasma: alveolar cell (AC), angiotensin-converting enzyme 2 (ACE2), atopic dermatitis (AD), ancestry clusters (AC1-4) granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF or GCSF), interleukin (IL), interferon (INF), monocyte chemoattractant protein 1 (MCP1), macrophage inflammatory proteins (MIP1 ), natural killer (NK), polymorphonuclear granulocyte (PMN), T-effector cell (TEFF cell), tumor necrosis factor (TNF), regulatory T cell (Treg cell). Mechanism of types of drugs and therapies useful in the treatment of SARS-CoV-2-infected patients [3,27,32].
- Subjects
MACROPHAGE colony-stimulating factor; IMMUNITY; TREATMENT effectiveness; GRANULOCYTES; SARS-CoV-2; MACROPHAGE inflammatory proteins; GRANULOCYTE-colony stimulating factor
- Publication
Journal of Personalized Medicine, 2022, Vol 12, Issue 6, p967
- ISSN
2075-4426
- Publication type
Correction Notice
- DOI
10.3390/jpm12060967