We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Chronic Microvascular Complication of Type 1 Diabetes Mellitus and Its Predictors Among Children with Type 1 Diabetes Mellitus in Ethiopia; A Single Center Experience: Ambi Directional Cohort Study.
- Authors
Eshetu, Konjit; Regassa, Lemma Demissie; Dehresa, Merga; Genete, Desta
- Abstract
This study aimed to assess the risk and predictors of chronic microvascular complication of type 1 diabetes mellitus among children with diabetes at Haramaya University Hiwot Fana Compressive Specialized Hospital from September 10, 2021 to January 30, 2023. Methods: A hospital-based Ambi directional cohort study was conducted. Survival data are described by follow-up time and Kaplan–Meier graph. To determine predictors associated with chronic microvascular complication we used a Poisson regression optimal model selected using the information criterion. All associations are tested at the 95% confidence level and a reported IRR P-value less than 0.05 is declared as a significant association between variables. Results: A total of 124 children with type 1 diabetes mellitus were followed with total 407.5 years risk time. The overall incidence rate of chronic microvascular complication was 83 per 1000 population per year (95% CI: 59− 116). The median time for detection of microvascular complication was 7 years after diagnosis. Being male with IRR 1.71 (95% CI: 0. 0.81– 3.56), being at pubertal age IRR 1.91 (95% CI: 1.05– 3.48), longer diabetes mellitus duration IRR 1.13 (95% CI: 1.07– 1.28), and poor glycemic control IRR 1.50 (95% CI: 0.46– 4.97) were found to be at higher risk for chronic microvascular complication. Conclusion: There was high incidence of chronic microvascular complication of diabetes mellitus. Being pubertal age group and more than 3 years duration after diagnosis had statistically significant association with complication.
- Subjects
ETHIOPIA; TYPE 1 diabetes; GLYCEMIC control; DIABETES complications; DIABETES in children; DIABETES; INSULIN pumps; CAPILLAROSCOPY
- Publication
Pediatric Health, Medicine & Therapeutics, 2024, Vol 15, p201
- ISSN
1179-9927
- Publication type
Article
- DOI
10.2147/PHMT.S456541