We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A phase I study of hepatic arterial infusion using difluoromethylornithine.
- Authors
Lipton, Allan; Harvey, Harold A.; Glenn, Jerry; Weidner, William A.; Strauss, Melvin; Miller, Sharon E.; Taylor, Jerlynn B.; White-Hershey, Deborah; Barlow, John L. R.; Lipton, A; Harvey, H A; Glenn, J; Weidner, W A; Strauss, M; Miller, S E; Taylor, J B; White-Hershey, D; Barlow, J L
- Abstract
Ten patients with metastatic disease to the liver were treated with difluoromethylornithine (DFMO) administered by continuous hepatic arterial infusion. Two of nine evaluable patients had an objective partial response. Stable disease was recorded in three patients. Ototoxicity was encountered in all patients who received a daily dose of DFMO equal to or greater than 1.0 g/m2.
- Publication
Cancer (0008543X), 1989, Vol 63, Issue 3, p433
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19890201)63:3<433::AID-CNCR2820630306>3.0.CO;2-5