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- Title
Ictal very low frequency oscillation in human epilepsy patients.
- Authors
Ren, Liankun; Terada, Kiyohito; Baba, Koichi; Usui, Naotaka; Umeoka, Shuichi; Usui, Keiko; Matsuda, Kazumi; Tottori, Takayasu; Nakamura, Fumihiro; Mihara, Tadahiro; Inoue, Yushi
- Abstract
The article presents a study on the carriers of leucine-rich repeat kinase 2 (LRRK2), a genetic determinant of Parkinson's disease (PD). It examines 52 relatives of PD patients who underwent clinical, neurological, and cognitive tests like Unified Parkinson's Disease Rating Scale (UPDRS) and gait assessment. Findings show that 25 patients were carriers of the LRRK2-G2019S mutation. It reveals that gait dynamics during challenging circumstances may serve as presymptomatic PD biological marker.
- Subjects
GENETIC mutation; GAIT in humans; COGNITIVE therapy; NEUROLOGY
- Publication
Annals of Neurology, 2011, Vol 69, Issue 1, p201
- ISSN
0364-5134
- Publication type
Article
- DOI
10.1002/ana.22158