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- Title
Rosai-Dorfman Disease of the Gastrointestinal Tract: Report of a Case and Review of the Literature.
- Authors
Alatassi, Houda; Ray, Mukunda B.; Galandiuk, Susan; Sahoo, Sunati
- Abstract
Rosai-Dorfman disease (RDD) is a rare, acquired disease of unknown etiology that affects primarily children and young adults. It is characterized by a proliferation of distinctive histiocytes in the lymph nodes and/or extranodal sites. Involvement of the gastrointestinal tract is rare. We report a case of RDD in a 60-year-old woman who presented with hematochezia and was found to have RDD of the rectum presenting as a rectal mass. This report highlights the current pathogenetic mechanisms, immunohistochemical markers, and the gastrointestinal manifestations of RDD.
- Subjects
GASTROINTESTINAL diseases; ETIOLOGY of diseases; LYMPH nodes; RECTUM; MACROPHAGES
- Publication
International Journal of Surgical Pathology, 2006, Vol 14, Issue 1, p95
- ISSN
1066-8969
- Publication type
Article
- DOI
10.1177/106689690601400119