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- Title
How can nanotechnology help to combat COVID-19? Opportunities and urgent need.
- Authors
Campos, Estefânia V. R.; Pereira, Anderson E. S.; de Oliveira, Jhones Luiz; Carvalho, Lucas Bragança; Guilger-Casagrande, Mariana; de Lima, Renata; Fraceto, Leonardo Fernandes
- Abstract
Incidents of viral outbreaks have increased at an alarming rate over the past decades. The most recent human coronavirus known as COVID-19 (SARS-CoV-2) has already spread around the world and shown R0 values from 2.2 to 2.68. However, the ratio between mortality and number of infections seems to be lower in this case in comparison to other human coronaviruses (such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV)). These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing.
- Subjects
MIDDLE East; MIDDLE East respiratory syndrome; COVID-19; MERS coronavirus; SARS disease; VIRUS diseases; SARS-CoV-2
- Publication
Journal of Nanobiotechnology, 2020, Vol 18, Issue 1, pN.PAG
- ISSN
1477-3155
- Publication type
Article
- DOI
10.1186/s12951-020-00685-4